background glioblastoma is a type of brain tumor with poor response to available therapies, and shows high rate of mortality. despite remarkable advancements in our knowledge about cytogenetic and pathophysiologic features of glioblastoma, current treatment strategies are mainly based on cytotoxic drugs; however, these therapeutic approaches are facing progressive failure because of the resista...

We present a Lagrangian for the bilinear discrete KP (or HirotaMiwa) equation. Furthermore, we show that this Lagrangian can be extended to a Lagrangian 3-form when embedded in a higher dimensional lattice, obeying a closure relation. Thus we establish the multiform structure as proposed in [8] in a higher dimensional case.

Island Parallel GA divides a population into subpopulations and assigns them to processing elements on a parallel computer. Then each subpopulation searches the optimal solution independently, and exchanges individuals periodically. This exchange operation is called migration. In this research, we propose a new algorithm that migrants are exchanged asynchronously among multiform subpopulations ...

Giant cell glioblastoma is an extremely rare variant of Glioblastoma (WHO grade IV) which is characterized by a predominance of bizarre, multinucleated giant cells. These tumors comprise of 0.8% of brain tumors and up to 5% of glioblastomas. In pediatric age group, these tumors are still uncommon with only around 53 published cases since 1952. Here, we report a case of a 12-year old female pat...

the median overall survival in glioblastoma multiforme is usually less than one year. long-term survival is rare and is seen in only 3%-6% of gbm patients. the present study reports the characteristics and treatment outcomes of six cases of glioblastoma multiforme with long-term survival. a literature review is also presented. between 1990 and 2008, 217 glioblastoma multiforme patients have bee...