This work proposes a flow system suitable for the rapid screening of formaldehyde contaminated in food. The system is based on the concept of a flow analyzer with a Hantzsch reaction. An operating procedure was developed for multiple tasking and high sample throughput. This resulted in a significant sample throughput of 51 samples h(-1). Under the optimized conditions, linear calibration from 1...

In this study, multi component Hantzsch reaction was carried out between various  Aromatic Aldehyde with Dimedone,Ethyl acetateand ammonium acetate to produce polyhydroquinolinederivatives under solvent-free conditions at 110oC by a (Zinc oxide  nanocatalyst) as effective Lewis acid. The remarkable advantages offered by this method compared with other methods are a green catalyst, simple work-u...

Within the realm of catalytic asymmetric hydrogenation, the focus continues to be on the use of chiral metal complexes in conjunction with a hydrogen source. Recently, the widespread development of organocatalysis, including the invention of iminium activation, has led to the discovery of many new enantioselective transformations. Based on this strategy, a number of bioinspired processes for th...

An efficient synthesis of polyhydroquinoline derivatives was reported via four-component coupling reactions of aldehydes, 1,3-dicarbonyl ketones (dimedone or 1,3-cyclohexanedione), ethyl acetoacetate or methyl acetoacetate and ammonium acetate in the presence of a catalytic amount of nanocrystalline TiO2 under solvent free conditions. The reported method is mild, rapid and has the advantages su...