When washed streptococci were incubated in a phosphate buffer containing MgSO4 and maltose (Bernheimer's basal medium) and centrifuged, no hemolytic activity was detected in the supernatant. Although incubation of the spent medium with carrier oligonucleotide did not yield active hemolysin, the mixture turned to be significantly hemolytic, upon ethanol precipitation and dehydration. Oxygen stab...

1. The evidence presented indicates that Mg(++), or other cation such as Ca(++), Ni(++), or Co(++), is essential for the hemolytic action of C'. Ca(++), Ni(++), and Co(++) are less effective than Mg(++). The hemolytic system usually does not contain sufficient Mg(++) for optimal hemolytic activity so that a marked enhancement can be obtained by addition of extra Mg(++). 2. The enhancing action ...

The humoral fluid of Branchiostoma belcheri tsingtauense was examined for the presence of complement-like activity. The humoral fluid showed hemolytic activity for rabbit erythrocytes and those from species representing mammals, birds, amphibians and fish, but not sensitized sheep erythrocytes. There was no relationship between phylogeny of the target erythrocytes and degree of hemolysis. The h...

Gemcitabine is a widely used drug in the treatment of diverse malignancies and its use has been approved by US Food Drug Administration. This associated with rare adverse event, Hemolytic Uremic Syndrome (HUS), characterized acute kidney injury, microangiopathic hemolytic anemia, thrombocytopenia. The purpose this report to draw attention an atypical manifestation severe unusual complication, d...

Since the turn of the century, Escherichia coli has been implicated in the etiology of weanling diarrhea (colibacillosis). However, rotavirus--a virus that destroys enterocytes--has been shown recently to be causally associated with weanling diarrhea of pigs. The role of both rotavirus and hemolytic enteropathogenic E. coli in weanling diarrhea was assessed in this study. Pigs from a closed her...

BACKGROUND Immune hemolytic anemia is a well-known complication after allogeneic hematopoietic stem cell transplantation (HSCT). Posttransplant hemolytic anemia results in increased red blood cell transfusions and medical sequelae including iron overload. CASE REPORT We present a case report of immune hemolytic anemia that occurred after allogeneic HSCT from an ABO major-mismatched, HLA-match...

Kimura’s disease (KD) is a rare chronic inflammatory disorder that involves the lymph nodes, skin, kidneys and ears, but its influence on the hematologic system remains unknown. We discovered a rare case of KD that developed hemolytic anemia. Erythrocytes hyperplasia with eosinophilia were observed in the bone marrow smears, while eosinophilic abscesses and endothelial proliferation could be fo...

Understanding the molecular mechanism of the interaction of amphipathic and antimicrobial peptides with membranes is of fundamental interest, especially because of the potential of amphipathic peptides as therapeutics. The most studied amphipathic peptides in this context are certainly melittin, magainin and alamethicin, of which melittin is the only one to exhibit a powerful hemolytic and ther...

Tragia involucrata commonly known as Indian stinging nettle is a shrub widely used in traditional ayurvedic system for treatment of cephalagia, skin infections, eczema, and bronchitis. However, in use as a traditional medicine since ancient time, its anti-arthritic and hemolytic properties are not yet studied. The present study aimed to assess the phytochemical analysis, in vitro anti-arthritic...