objective(s): streptococcus pyogenes produces extracellular hyaluronidase enzyme. this enzyme is directly associated with the spread of the organism during infection. the objective of the present study was to clone and express the nucleotide sequence of the enzyme which is involved in hyaluronidase enzymatic activity. materials and methods: the enzymatic region of hyaluronidase gene was detecte...

Background: Atypical hemolytic uremic syndrome (aHUS) is a life-threatening and scarce disorder characterized by acute renal failure and disease, non-immune microangiopathic hemolytic anemia and thrombocytopenia, leading to end-stage renal failure or death, and consequently maybe accompanying by extra renal manifestations. Case report: We reported aHUS accompanied by autoimmune hemolytic anemi...

abstract background and objective: snake venom is a complex of several toxic elements and enzymes. it has the agents with the ability to destroy cellular and subcellular membrane and to bring about hemolysis of red blood cells (rbc). two types of direct and indirect hemolytic activity are known in snake venom in that phospholipase a2 is responsible for the indirect lysis. the aim of this study ...

background: sodium bicarbonate serum therapy is used for compensation bicarbonate lost and increasing blood ph in metabolic acidosis caused by severe anemia in patient with glucose-6-phosphate dehydrogenase (g6pd) deficiency. the aim of present study was comparison the effect of serum therapy using two different serums (serum with bicarbonate and without bicarbonate) on some renal and hematolog...

introduction autoimmune haemolytic anemia (aiha) is a complex process characterized by an immune reaction against red blood cell self-antigens. the analysis of specimens, drawn from patients with cold auto-immune hemolytic anemia is a difficult problem for automated hematology analyzer. this paper was written to alert technologists and pathologists to the presence of cold agglutinins and its ef...

life-long red blood transfusion remains the main treatment for severe thalassemia. the development of hemolytic alloantibodies and erythrocyte autoantibodies complicated transfusion therapy in thalassemia patients. the frequency causes and prevention of this phenomenon among 80 transfused thalassemia patients were evaluated in ali asghar children's hospital during 1998-2004 in a cross-sectional...

nine hundred and twelve, consecutive patients attended various clinics of isfahan university for various complains have been evaluated for a.s.o. titers among whom 172 has positive nasopharyngeal cultures for type a, b hemolytic streptococcus. all of the patients with positive cultures have a.s.o. titers of above 333 todd’s unit, while with exception of 22 cases all of the others had values of ...

The article presents the results of a clinical and bacteriological assessment pharmacological efficacy 1,3-diethylbenzimidazolium triiodide in chronic compensated tonsillopharyngitis. As result 10-day course treatment, an improvement status patients was achieved, as well significant positive effect on composition pharyngeal microbiocenosis. In particular, content Staphylococcus aureus, β-hemoly...

background and objective: hemolytic uremic syndrome (hus) is the most prevalent cause of children renal insufficiency which in many cases (90%) occurs following diarrhea. hemolytic microangiopathic anemia, thrombocytopenia, and renal insufficiency are main symptoms of hemolytic uremic syndrome. this study aims to consider the relationship between pathologic data of nephro-biopsy and laboratory ...