نتایج جستجو برای: histone like protein
تعداد نتایج: 1804323 فیلتر نتایج به سال:
DNA methylation and histone modifications are important epigenetic markers involved in transcriptional gene regulation in animals and plants. In Arabidopsis, IDM1 is a histone acetyltransferase that plays critical roles in preventing hypermethylation of DNA and transcriptional gene silencing, but the mechanism(s) by which IDM1 is targeted to specific genomic loci is still unclear. Here, we find...
DNA methylation is an essential epigenetic mark in mammals that has to be re-established after each round of DNA replication. The protein UHRF1 is essential for this process; it has been proposed that the protein targets newly replicated DNA by cooperatively binding hemi-methylated DNA and H3K9me2/3, but this model leaves a number of questions unanswered. Here, we present evidence for a direct ...
Geminiviruses constitute a group of plant viruses, with a ssDNA genome, whose replication in the nucleus of an infected cell requires the function of geminivirus-encoded replication initiator protein (Rep). Our results suggest that monoubiquitinated histone 2B (H2B-ub) promotes tri-methylation of histone 3 at lysine 4 (H3-K4me3) on the promoter of Chilli leaf curl virus (ChiLCV). We isolated ho...
Centromeric H3-like histones, which replace histone H3 in the centromeric chromatin of animals and fungi, have not been reported in plants. We identified a histone H3 variant from Arabidopsis thaliana that encodes a centromere-identifying protein designated HTR12. By immunological detection, HTR12 localized at centromeres in both mitotic and meiotic cells. HTR12 signal revealed tissue- and stag...
Histones are small polycationic proteins complexed with DNA located in the cell nucleus. Upon apoptosis they are secreted from the cells and react with extracellular polyanionic compounds. Actin which is a polyanionic protein, is also secreted from necrotic cells and interacts with histones. We showed that both histone mixture (histone type III) and the recombinant H2A histone bundles F-actin, ...
در این مطالعه از توالی ژن های mating type و histone h3 جهت بررسی روابط فیلوژنتیکی گونه های قارچ fusarium graminearum sensu lato جدا شده از نمونه خاک های مناطق مختلف جغرافیایی ایران شامل نواحی شمالی، نواحی جنوبی و نواحی شمال غربی استفاده شده است. برای تکثیر نواحی mating type از آغازگرهای m12-2/m12-3 و m21-1/m21-2 و برای تکثیر ژن histone h3 از آغازگرهای h3f1/h3r1 استفاده شد. قطعات تکثیر شده توالی...
lncrnas (long non-coding rnas) are responsible to control the degradation process, rna stability, orchestration, inhibition, transcription and histone modification etc. these rnas have been termed as the key agents of several mechanisms such as development, organogenesis and regeneration of damaged tissues etc. they interact with a number of partner molecules either protein, rnas or dnas and co...
Chromatin remodeling mediated by histone acetylation might be involved in the pathophysiology and the treatment of depression. Recently, it has been reported that the histone deacetylase (HDAC) inhibitors, such as sodium butyrate (SB), could be a potential therapeutic agent for depression treatment. In the present study, we aimed to clarify the antidepressant mechanism of SB in the hippocampus....
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