Pteris vittata L., a fern was evaluated for its alpha amylase inhibitory potential owing to its previously reported antihyperglycemic activity. This Pteridophyte was also assayed for its free radical inhibition ability in ABTS decolourisation assay followed by quantification and HPTLC of polyphenols. The Porcine pancreatic alpha amylase inhibition was studied invitro and compared with standard ...

A new, simple, accurate, and precise high-performance thin-layer chromatographic (HPTLC) method has been established for simultaneous analysis of valsartan and hydrochlorothiazide in tablet formulations. Standard and sample solutions of valsartan and hydrochlorothiazide were applied to precoated silica gel G 60 F254 HPTLC plates and the plates were developed with chloroform–ethyl acetate–acetic...

We have developed a simplified and improved high performance liquid chromatography (HPLC) method for the detection and quantitation of tissue lipid using a new laser light-scattering detector (Varex model ELSD II). This detector has a limit of sensitivity of 50 ng for neutral lipid and 200 ng for most phospholipids with excellent reproducibility. By coupling the ELSD II with a ternary gradient ...

Ginger rhizome powder is widely used as a food spice and an herbal medicine around the world. A sensitive and accurate High Performance thin layer chromatographic (HPTLC) method has been developed to determine the quantity of 10-gingerol in Zingiber officinale extract and ginger-containing dietary supplements, teas and commercial creams on aluminum-backed silica gel 60 F254 plates with n-hexane...

A new stability-indicating reversed-phase high-performance thin-layer chromatographic (RP-HPTLC) method for densitometric analysis of thiocolchicoside was developed and validated. The chromatograms were developed using aluminum plates pre-coated with silica gel 60 RP-18 F254S as a stationary phase and methanol : water (70 : 30 v/v) as a mobile phase. The compact band for thiocolchicoside was ob...

Objective: The aim of this paper is to create a new, systematic high-performance thin-layer chromatography (HPTLC) method for ciprofloxacin that based on quality by design (QbD). Methods: mobile phase was chloroform: IPA: H2O: Formic Acid (2:7:0.5:0.5V/V), and the chromatographic separation performed aluminum-backed silica gel 60 F254 plates. Ciprofloxacin detected using UV light at 278nm. In f...

"Corrigendum to: High performance thin layer chromatography (HPTLC) method development and validation for the simultaneous determination of paracetamol, caffeine, chlorpheniramine phenylepherine in tablet formulation" published on 11 Aug 2022 by Akadémiai Kiadó.

Analytical methodologies are critical throughout the medicine development process, including marketing and post-marketing studies. The advancement of bio-analytical techniques has resulted in a dynamic field with many exciting potentials for further future. Bio-analysis is commonly utilised pharmaceutical drug drug's its metabolites' quantitative levels. goal to undertake pharmacokinetic pharma...

Nowadays, plants have been considered as powerful agents for treatment of disorders regarding to their traditional use. In Iranian Traditional Medicine (ITM), plants have a special role in the treatment of various diseases. Burns with their devastating outcomes have been discussed in ITM as well. In the present study, a polyherbal ointment (PHO), retrieved from ITM, was formulated for burn heal...