23 Neutrophil (PMNL) influx precedes lung macrophage (LM) influx into the lung following 24 exposure of newborn pups to 60% O2. We hypothesized that PMNL were responsible for the 25 signals leading to LM influx. This was confirmed when inhibition of PMNL influx with a CXC 26 chemokine receptor-2 antagonist, SB-265610, also prevented the 60% O2-dependent LM influx, 27 LM-derived nitrotyrosine fo...

A correlation is made between the appearances of the nexus ("gap junction") as revealed by thin-section and by freeze-cleave electron microscopy techniques. These methods reveal different aspects of a complex subunit assembly forming the nexus membranes. In thin sections, the nexus is formed by the very close apposition of two "unit" membranes. The electron-opaque tracer, colloidal lanthanum hy...

In situ measurements of velocity and size distributions of initially monodisperse water mists of initial diameters ranging from 14 lm to 42 lm seeded into the air stream of non-premixed propane/air counterflow flames are reported. Droplets were generated piezoelectrically, and the size and velocity distributions and the number density were determined by phase-Doppler particle anemometry. Drople...

PURPOSE To date, response criteria and optimal methods for assessment of outcome have not been standardized in patients with leptomeningeal metastasis (LM). METHODS A Response Assessment in Neuro-Oncology working group of experts in LM critically reviewed published literature regarding randomized clinical trials (RCTs) and trial design in patients with LM. RESULTS A literature review determ...

Chick-mouse heterokaryons were obtained by UV-Sendai virus-induced fusion of chick erythrocytes with thymidine (dT) kinase-deficient mouse fibroblast [LM(TK(-))] cells. Autoradiographic studies demonstrated that 1 day after fusion, [(3)H]dT was incorporated into both red blood cell and LM(TK(-)) nuclei of 23% of the heterokaryons. Self-fused LM(TK(-)) cells failed to incorporate [(3)H]dT into n...

Let M be a closed, oriented manifold of dimension d. Let LM be the space of smooth loops in M . In [2] Chas and Sullivan defined a product on the homology H∗(LM) of degree −d. They then investigated other structure that this product induces, including a Lie algebra structure on H∗(LM), and an induced product on the S 1 equivariant homology, H S ∗ (LM). These algebraic structures, as well as oth...

When considering the use of layered manufacturing (LM), there are many issues a designer has to address for handling a stereolithography tessellation language (STL) model, the de facto standard for LM. In this paper, we propose an Internet-based design visualization tool for decision support when optimizing the LM process in support of a highly interactive and collaborative virtual environment ...

BACKGROUND The aim of this study was to evaluate the efficacy of laser myringotomy (LM) compared to ventilation tube (VT), and to assess the clinical success criteria of LM-assisted VT insertion as the flexible alternatives avoiding GA for the treatment of bilateral consistent otitis media with effusion (OME). METHODS AND FINDINGS LM under topical anesthesia was followed by VT insertion in co...

BACKGROUND Myocarditis is an uncommon but serious manifestation of systemic lupus erythematosus (SLE). This study aimed to investigate clinical characteristics and outcomes of lupus myocarditis (LM) and to determine risk factors of LM in hospitalized Chinese patients with SLE. METHODS We conducted a retrospective case-control study. A total of 25 patients with LM from 2001 to 2012 were enroll...