Background: Gallium-66 (T1/2= 9.49 h) is an interesting radionuclide that has potential for positron emission tomography (PET) imaging of biological processes in intermediate to slow target tissue uptake. Oxine has been labeled with this radioisotope in the form of [66Ga]gallium chloride for its possible diagnostic properties. Materials and methods: 66Ga was produced in the 30 MeV cyclotron (Cy...

Introduction: To increase the radiation therapy efficiency, two approaches have been employed which include increasing the dose delivery or modifying the biological response to ionizing radiation. This study aimed to modify the biological response to ionizing radiation by combination therapy using radio-sensitizer agent and anticancer drug. Materials and Methods:</str...

Background: While assisted reproductive techniques (ARTs) are considered to be safe, many concerns exist about the safety of these techniques. Two important and indispensable parts of these techniques are in vitro culture and vitrification. While much progress has been made in developing culture conditions, it remains suboptimal. In order to investigate the effect of culture medium on in vitro ...

      A series of angiotensin II (A II) receptor antagonist of some substituted 5-(biphenyl-4-ylmethyl) pyrazole were subjected to QSAR analysis using Hansch and Fujita-Ban model, by using combination of thermodynamic, electronic, spatial descriptor and presence or absence of substituent respectively. Several QSAR model were obtained using stepwise regression analysis. Two models from both the ...

background: gallium-66 (t1/2= 9.49 h) is an interesting radionuclide that has potential for positron emission tomography (pet) imaging of biological processes in intermediate to slow target tissue uptake. oxine has been labeled with this radioisotope in the form of [66ga]gallium chloride for its possible diagnostic properties. materials and methods: 66ga was produced in the 30 mev cyclotron (cy...

in this study, the synthesis of 4 h -chromenes of biological activity via a multicomponent reaction of dimedone, aromatic aldehydes and malononitrile catalyzed by glutamic acid as a catalyst was investigated. the structural features of the synthesized compounds were characterized by melting point, ir and 1 h nmr analysis. the catalyst being reported here is cheap, safe to handle and the whole p...

in present studies the synthesis, characterization and biological properties ofoxovanadium(iv) coordination compounds of 4[n-(4′-ethylbenzalidene)amino] antipyrinethiosemicarbazone (ebaapts) and 4[n-(2′,4′-dimethylbenzalidene)amino] antipyrinethiosemicarbazone (dmbaapts) with the general composition vox2l (x = c1-, br-, i-, no3-or ncs-) and vo(cio4)2(l)h2o (l = ebaapts or dmbaapts) are describe...

introduction: widespread medical usage of botulinum toxins has increased the need for the precise analysis of its biological activity. the aim of this study was production and crystallization of the botulinum type a toxins. methods: in this study, clostridium botulinum was grown and inoculated into the tripticase soya broth culture media, under anaerobic condition and toxin production was monit...