background: supplementation of luteal phase with progesterone is prescribed for women undergoing routine ivf treatment. objective: the objective of this study was to compare the efficacy of three types of progesterone on biochemical, clinical and ongoing pregnancy rates and abortion and live birth rates. materials and methods: a prospective randomized study was performed at royan institute betw...

background: endometriosis is a common hormone-dependent gynecologic disease with a high recurrence. laparotomy or laparoscopy is the standard surgery for the large endometrioma. also, sclerotherapy is basically used to treat different diseases one of which is endometrioma. objective: the study was designed to assess the value of transvaginal ultrasound-guided ethanol sclerotherapy in patients w...

Objective(s) The use of co-culture cells as well as extra cellular matrix are among those strategies that have been employed to direct mesenchymal stem cell (MSC) bone differentiation in culture. In this regard, there is no study considering the effects of Matrigel on mesenchymal stem cell (MSC) in vitro bone differentiation. This was the subject of the present study. Materials and Methods ...

In addition to its antioxidant effect, Vitamin E or α–tocopherol is suggested to enhance remyelination in the animal model of non-inflammatory demyelination. In this study, the possible proliferative effect of vitamin E on human- induced pluripotent stem cell-derived neural progenitors (hiPS-NPs) and the underlying mechanisms were investigated in vitro. NPs were induced from iPS cells via 3 ste...

experimental  autoimmune  encephalomyelitis (eae)  is  a  mouse  model  for  multiple sclerosis (ms), this autoimmune disease is mainly mediated by adaptive and innate immune responses that lead to an inflammatory demyelination and axonal damage. imatinib mesylate is a  selective protein  tyrosine kinase inhibitor  with immunomodulatory  properties  that abrogates multiple signal transduction p...

Several new superior apricot × plum (Prunus armenica × P. domestica) inter specific hybrid rootstocks have been recently produced in Iran, but the propagation of these hybrids by conventional means has been shown to be very difficult. In vitro propagation could be a reliable method for mass clonal propagation of these new rootstocks. In this study, in vitro establishment, proliferation and root...

Objective(s): The study aimed to investigate the effects of adrenomedullin (ADM) and proadrenomedullin N- terminal 20 peptide (PAMP) on angiotensin II (AngII)-stimulated proliferation in vascular smooth muscle cells (VSMCs). Materials and Methods: Thoracic aorta was obtained from Wistar rats and VSMCs were isolated from aorta tissues and then cultured. In vitro cultured VSMCs were stimulated w...

objective(s) it is believed that the mesenchymal stem cell (msc) differentiation and proliferation are the results of activation of wnt signaling pathway. on the other hand, lithium chloride is reported to be able to activate this pathway. the objective of this study was to investigate the effect of lithium on in vitro proliferation and bone differentiation of marrow-derived msc. materials and ...