Diabetes mellitus has become a signifi cant health problem throughout the world, where it constitutes the underlying cause for 84% of lower limb amputations due to recalcitrant ulcers. The Center for Genetic Engineering and Biotechnology (CIGB) at Havana, Cuba has designed an integrated strategy for preclinical testing, pharmaceutical development, production, clinical trials and business negoti...

healthcare and Ranbaxy have been bought by Abbott and Daiichi Sankyo, respectively.[3] Cipla, an indigenous company, lone with a market share of about 5.4% tops the list of top 10 companies in India. The increasing presence of foreign companies among the top pharmaceutical companies in India is may be due to a few buyouts which happened in the recent past. Daiichi Sankyo, a leading Japanese pha...

BACKGROUND Yaws, one of the 17 neglected tropical diseases (NTDs), is targeted for eradication by 2020 in resolution WHA66.12 of the World Health Assembly (2013) and the WHO roadmap on NTDs (2012). The disease frequently affects children who live in poor socioeconomic conditions. Between 1952 and 1964, WHO and the United Nations Children's Fund (UNICEF) led a global eradication campaign using i...

BACKGROUND More than 40 million women use injectable contraceptives to prevent pregnancy, and most current or previous injectable users report being satisfied with the method. However, while women may find injectables acceptable, they may not always find them accessible due to stock-outs and difficulties with returning to the clinic for reinjections. FHI 360 is spearheading efforts to develop a...

Abstract Abstract Background: Availability and affordability of medicines are crucial to achieving success in prevention programs, particularly in developing countries. Objective: The aim of this study was to determine the availability and affordability of cardiovascular medicines for secondary prevention in Tehran province of Iran. Methods: A cross-sectional survey was conducted in Tehran pro...

The number of commercially available injectable soft tissue fillers has increased dramatically over the past decade. In the United States, a variety of temporary fillers have received Food and Drug Administration (FDA) approval. However, at the present time, there are no permanent soft tissue injectable fillers available. This article will discuss the authors' experience with some of the more p...

A total of 197 multidose injectable vials were collected from 10 different nursing stations and evaluated for sterility. Experimental contamination studies were undertaken, and the cost-effectiveness of multidose vials was compared with that of single-dose vials. Our results showed that bacterial contamination of multidose injectable vials was not a significant hazard; in addition, contrary to ...

Injectable Hydrogels In article number 2101284 by Chien-Chi Lin and co-workers, a biocompatible pH/thermo dual responsive injectable hydrogel is synthesized reversible addition-fragmentation chain-transfer (RAFT) polymerization acylhdrazone click chemistry. Upon injection, sol-gel transition occurs rapidly at body temperature the porous hydrogels degrade slowly under mild acidic condition due t...

Horseshoe crabs have been a model for many biomedical science studies. Medicinal value of horseshoe crabs comes from its blue blood, eye and exoskeleton (chitin). Ability of blood to clot in the presence of bacteria, rendering the bacteria harmless has created its biomedical importance. Blood cells (amebocytes) carry Factor C, which binds lipopolysaccharide (LPS), undergoes a structural reorgan...