نتایج جستجو برای: innate response
تعداد نتایج: 1004450 فیلتر نتایج به سال:
Journal:
:Journal of Neuropathology & Experimental Neurology
2008
2017
Souparno Bhattacharya
Kalayarasan Srinivasan
Salim Abdisalaam
Fengtao Su
Prithvi Raj
Igor Dozmorov
Ritu Mishra
Edward K. Wakeland
Subroto Ghose
Shibani Mukherjee
Aroumougame Asaithamby
RAD51, a multifunctional protein, plays a central role in DNA replication and homologous recombination repair, and is known to be involved in cancer development. We identified a novel role for RAD51 in innate immune response signaling. Defects in RAD51 lead to the accumulation of self-DNA in the cytoplasm, triggering a STING-mediated innate immune response after replication stress and DNA damag...
Journal:
:Science
2009
Journal:
:Current Opinion in Genetics & Development
2017
Journal:
:Paediatric Respiratory Reviews
2008
Journal:
:Nature Reviews Rheumatology
2012
Journal:
:Experimental Dermatology
2013
Journal:
:Applied and Environmental Microbiology
2013
Journal:
:Journal of Experimental Medicine
2003
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