Implantable cardiac defibrillators (ICDs) and cardiac resynchronization therapy (CRT) devices have had a significant favourable impact on hospitalization and mortality among patients with heart failure (HF). Despite some degree of overlap, the therapeutic rationales for these two forms of device-based therapies are distinct, where ICDs abort arrhythmic death and CRT devices improve cardiac func...

Results We present the results of 87 patients with acute angiocholitis, evaluated and treated by a multidisciplinary team. The results are influenced mainly by the multiple therapeutic options and especially by how they were set for this pathology, for which there is no gold standard regarding the treatment. The particularity of this study stems from the fact that although all patients were ini...

This paper presents a study of successive new product introductions in the mature tennis racket industry. The inquiry examines novel design’s important role in strategic renewal, under the assumption that innovation includes not only the development, production, and launch of new products, but also communication between firms and market. We explore this industry’s transformation through the str...

Deep structural and sustained change is necessary to tackle contemporary environmental challenges. How such change emerges and can be governed has been explored through the notion of sustainable innovation journeys. To date research had conceptualised such journeys as transitions to more sustainable socio-technical systems, e.g. mobility, shelter, food and farming. However, there is a paucity o...

This paper develops a mathematical model of innovation in technology with two main characteristics. First, it discusses the endogenously made decision on not only how much to innovate, but also, how much to imitate. Second, it demonstrates that the decision to innovate or imitate are not mutually exclusive and a firm can innovate and imitate simultaneously. A mathematical model is presented, an...

Unrelenting innovation is the most enduring source of growth, profit, and competitive advantage for firms today. Market leaders are in the best position to innovate because of their deep pockets, rich talent, and intimate knowledge of the market. Yet, throughout history major companies have stumbled, declined sharply, or gone bankrupt due to a failure to innovate. Examples in only the last few ...

Suppose an intermediary provides a benefit to buyers when they purchase from sellers using the intermediary’s technology. We develop a model to show that the intermediary would want to restrict sellers from charging buyers more for transactions it intermediates. With this restriction an intermediary can profitably raise demand for its services by eliminating any extra price buyers face for purc...

University curricula in Information Technology (IT) necessarily require frequent change, updating and even complete revision due to advances in technologies, new methodologies, and changes in how people and organisations make use of computers. We argue that curriculum change, which is a complex process that involves many actors, should be seen through the lens of innovation theory and studied a...

abstract This paper consolidates the state of academic research on innovation. Based on a systematic review of literature published over the past 27 years, we synthesize various research perspectives into a comprehensive multi-dimensional framework of organizational innovation – linking leadership, innovation as a process, and innovation as an outcome. We also suggest measures of determinants o...