to determine the addition of value of neoadjuvant, concurrent and adjuvant chemotherapy to radiation in the treatment of nasopharyngeal carcinoma with regard to the overall survival (os) and disease free survival (dfs) within a six year period in tehran cancer institute. files of all patients with nasopharyngeal carcinoma treated by radiotherapy with or without concurrent chemotherapy in a cura...

context to review and summarize the literature regarding the current status of postchemotherapy laparoscopic retroperitoneal lymph node dissection (pcl-rplnd) in patients with testicular germ cell tumor. evidence acquisition a comprehensive review of the english literature was performed using the pubmed database using the terms “laparoscopy” or “laparoscopic”, retroperitoneal lymph node dissect...

leiomyosarcoma is a rare entity in prostate but it is the most common type of prostate sarcomas in adult patients. in most reported series the prognosis is poor and the median survival is about 15-18 months. hereby we present a 72 years old man who received combined modality treatment including radical surgery followed by adjuvant chemotherapy and radiotherapy. he has been well for 14 months, b...

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Children with acute lymphoblastic leukemia (ALL) who have completed 2.5 to 3 years of initial chemotherapy have an off-therapy relapse rate of approximately 20%. In an attempt to improve the survival of children with a late bone marrow (BM) relapse (ie, occurring greater than 6 months after cessation of primary therapy), the Pediatric Oncology Group designed a randomized study to compare the ef...

BACKGROUND AND OBJECTIVE In multiple myeloma (MM) patients treated with conventional chemotherapy, the attainment and duration of a plateau phase seems to affect survival more than the degree of response to initial treatment. The aims of this study are: 1) to analyze within a cohort of previously untreated MM patients the incidence and the duration of the plateau phase; 2) to correlate it with ...

Drug resistance leads to chemotherapy failure and is responsible for the death of a great majority of patients with metastatic, late-stage ovarian cancer. The present study addressed whether changes in the chemotherapy dosing schedule affect the development, further worsening, or circumvention of drug resistance in chemosensitive and chemoresistant ovarian cancer. Severe combined immunodeficien...

intravenous chemotherapy is an important mean for the treatment of cancers. infusion phlebitis (ph) is a common and acute complication of chemotherapy. the frequency of ph is about 70% in patients undergoing chemotherapeutic management. it can induce the pain, increase the risk of thrombophlebitis, lead to incomplete follow-up, and thereby, affect the patient’s health status. respecting the gre...

introduction: cancer and chemotherapy could decrease serum zinc level. in this study, serum zinc level was investigated at the beginning of cancer diagnosis and 3 months after chemotherapy in children with all types of cancer. method: in this cross sectional study forty-five 1-15 year old children who were newly diagnosed cancer cases (leukemia, lymphoma and solid tumor) were evaluated. patient...