Cationic amphiphilic polymethacrylate derivatives (PMAs) have shown potential as a novel class of synthetic antimicrobials. A panel of PMAs with varied ratios of hydrophobic and cationic side chains were synthesized and tested for antimicrobial activity and mechanism of action. The PMAs are shown to be active against a panel of pathogenic bacteria, including a drug-resistant Staphylococcus aure...

The in vitro and in vivo antimicrobial activity of primary ammonium ethyl methacrylate homopolymers (AEMPs) was investigated. AEMPs with different degrees of polymerization (DP = 7.7-12) were prepared by reversible addition-fragmentation chain-transfer (RAFT) polymerization. The AEMPs showed higher inhibitory effects against Gram-positive bacteria, including methicillin-resistant Staphylococcus...

The mononuclear cobalt(III) complex derived from 1,10-phenanthroline and maltose ([Co(phen)2maltose]Cl2∙3H2O) (1) has been synthesized and characterized in aqueous solution. Its characterization was based on its optical and spectroscopic properties. The antimicrobial activity of this complex was screened in vitro against the microorganisms Escherichia coli DH5a, Salmonella enterica sv Enteritid...

Male and female leaves and fruits of eleven different taxons of Iranian conifers (Cupressus sempervirens var. horizontalis, C. sempervirens var. sempervirens, C. sempervirens cv. Cereifeormis, Juniperus communis subsp. hemisphaerica, J. excelsa subsp. excelsa, J. excelsa subsp. polycarpos, J. foetidissima, J. oblonga, J. sabina, Platycladus orientalis and Taxus baccata) were collected from diff...

Male and female leaves and fruits of eleven different taxons of Iranian conifers (Cupressus sempervirens var. horizontalis, C. sempervirens var. sempervirens, C. sempervirens cv. Cereifeormis, Juniperus communis subsp. hemisphaerica, J. excelsa subsp. excelsa, J. excelsa subsp. polycarpos, J. foetidissima, J. oblonga, J. sabina, Platycladus orientalis and Taxus baccata) were collected from diff...

in this study bactericidal activity of a malodor neutralizer containing silver nanoparticles manufactured in iran has been tested. for this purpose different concentrations of the product encounter with staphylococcus aureus, pseudomonas aeruginosa and bacillus cereus then the activity were evaluated in different contact times. the products containing at least 200 ppm of silver nanoparticles we...

The aim of the present investigation was to assess and compare the antimicrobial activities of the lemon (Citrus sinensis) peel extract and lemon oil against common food borne pathogens and to study their potential as food bio-preservatives. The antagonistic activity of lemon peel extract and lemon oil was studied against common food borne pathogens like Staphylococcus aureus, Staphylococcus ep...

A series of substituted chalcones and pyrimidine derivatives on their base was synthesized. Obtained compounds were tested for antimicrobial activity ability to increase known substances. Pyrimidine products shown good against Staphylococcus aureus Candida tropicalis. These also could modified polyguanidines aureus.

Bacteria subvert the immune system by suppressing antimicrobial responses or directly killing immune cells. A new study shows that Staphylococcus aureus can also turn antimicrobial responses to its advantage by converting neutrophil extracellular traps into a bacterial weapon against macrophages.