In this issue of The Journal , Liew, et al present a cross-sectional study comparing the 10-year atherosclerotic cardiovascular disease (ASCVD) risk score in patients with axial spondyloarthritis (axSpA) versus general US population. Their hypothesis was that diagnosis axSpA would be associated higher ASCVD1. They studied participating 2 different cohort studies (followed at University Califor...

The World Health Organisation has declared the period 2000 to 2010 the Bone and Joint Decade. This is indeed timely and appropriate. Hundreds of millions of people in the world today are beset with a host of disabilities caused by trauma, ageing and degeneration and other affections of the musculo-skeletal system. With the state of art of orthopaedic surgery and rheumatology, sufferers of bone ...

Rare diseases represent an important public-health issue, affecting 26-30 million persons across Europe, and a major challenge for research. The fragmentation of resources and knowledge for the 6000-8000 rare diseases and the lack of efficient treatments for many of them necessitate a coordinated European approach to unravel the underlying molecular defects and pathophysiological mechanisms. Th...

Canine osteoarthritis (OA) commonly occurs in association with articular diseases, such as hip dysplasia (HD), elbow dysplasia (ED), or cranial cruciate ligament rupture (CCLR). We hypothesized that a common genomic risk for the development of canine joint disease and canine OA would be identified by evaluating the allele frequencies of candidate gene single nucleotide polymorphisms (SNPs) in d...

OBJECTIVE To analyse the changes in synovial fluid (SF) in the most common knees joint diseases, and to establish a relationship according to its concentration. MATERIAL AND METHODS A total of 62 synovial fluids were analysed from knees with, meniscus disease (32), anterior cruciate ligament (ACL) (17) and isolated chondral injury (13). A quantitative and quality study was performed on each s...