The intestinal resident Candida glabrata opportunistically infects humans. However few genetic factors for adaptation in the intestine are identified in this fungus. Here we describe the C. glabrata CYB2 gene encoding lactate dehydrogenase as an adaptation factor for survival in the intestine. CYB2 was identified as a virulence factor by a silkworm infection study. To determine the function of ...

The current study was designed to estimate the pork quality traits using metabolites from exsanguination blood and postmortem muscle simultaneously under the Korean standard pre- and post-slaughter conditions. A total of 111 Yorkshire (pure breed and castrated male) pigs were evaluated under the Korean standard conditions. Measurements were taken of the levels of blood glucose and lactate at ex...

salt tolerance in crops is multigenic in nature and quantitatively inherited, and therefore controlled by minorgenes. to study the diversity of qtls conferring salt tolerance in barley, four barley mapping populations including l94 × vada (l × v, 103 rils), oregon wolf barley (owb) (dom × rec, 94 dhs), susptrit × vada (su × v, 152 lines), and susptrit × cebada capa (su × cc, 113 lines) were tes...

Lactate accumulation in tumors has been associated with metastases and poor overall survival in cancer patients. Lactate promotes angiogenesis and metastasis, providing rationale for understanding how it is processed by cells. The concentration of lactate in tumors is a balance between the amount produced, amount carried away by vasculature and if/how it is catabolized by aerobic tumor or strom...

Let N = f1; 2; : : : ; ng and c 2 Rn: A k-tuple (t1; : : : ; tk) of elements in N is called an acceptable cell if 1 k Xi=1 cti 1: We consider the problems of (i) nding the set T of all acceptable cells e ciently (ii) nding a maximum number of mutually disjoint acceptable cells. The latter problem is called k-packing under tolerance constraints. For both problems, heuristics and exact solution a...

The link between lactate generation and cellular acidosis has been questioned based on the possibility of H+ generation, independent of lactate production during glycolysis under physiological conditions. Here we test whether glycolytic H+ generation matches lactate production over a physiological pH and lactate range using ischemia applied to the hindlimb of a mouse. We measured the H+ generat...

the aim of this study was to determine the effects of sodium bicarbonate supplementation on blood lactate level and anaerobic power of futsal players. 24 futsal players (mean age of 15.88±1.59 years, weight 62.02±12.76 kg, height 173.21±8.23 cm, bmi 20.51±3.33 kg/m2) were selected and randomly divided into two groups (experimental, n=12) and (control, n=12). the protocol consisted of a five-min...