نتایج جستجو برای: laryngeal mucoepidermoid carcinoma
تعداد نتایج: 407202 فیلتر نتایج به سال:
PURPOSE Laryngeal carcinomas always resist to radiotherapy. Hypoxia is an important factor in radioresistance of laryngeal carcinoma. Glucose transporter-1 (GLUT-1) is considered to be a possible intrinsic marker of hypoxia in malignant tumors. We speculated that the inhibition of GLUT-1 expression might improve the radiosensitivity of laryngeal carcinoma. METHODS We assessed the effect of GL...
The biologic behavior and factors influencing the development of salivary gland mucoepidermoid carcinoma are not fully understood. Alteration of the cyclin-dependant kinase inhibitor p21(WAF) could cause uncontrolled proliferation leading to cancer. Thirty-five mucoepidermoid carcinomas were graded and immunohistochemically stained for p21(WAF). The percentage of positive tumor cells was determ...
Background and purpose: Salivary gland neoplasms are heterogeneous and have low prevalence. Hematoxylin- eosin staining is used for their diagnosis, however, sometimes diagnosis may not be made by this method, so other methods are necessary. The aim of this study was to determine whether morphometry is an appropriate method in differentiating benign and malignant salivary tumors or not. Mate...
Introduction: Malignant tumors of larynx, mostly seen in males, are usually observed during the fifth and sixth decades of life. These tumors are usually associated with tobacco and alcohol usage. The symptoms of these tumors are hoarseness, dysphagia and a chronic sore throat. A rare form of laryngeal malignancy is adenoid cystic carcinoma as a malignant minor salivary gland tumor. Case Re...
To discover candidate biomarkers for diagnosis and detection of human laryngeal carcinoma and explore possible mechanisms of this cancer carcinogenesis, two-dimensional strong cation-exchange/reversed-phase nano-scale liquid chromatography/mass spectrometry analysis was used to identify differentially expressed proteins between the laryngeal carcinoma tissue and the adjacent normal tissue. As a...
BACKGROUND Cancer is a multifactorial disease. Repetitive cumulative damage of cellular organelles by oxy-free radicals are few of the important causative factors. AIM To assess the role of oxidative stress in the laryngeal cancer patients in Indian population. SETTING AND DESIGN Case control study. MATERIALS AND METHODS Level of malondialdehyde (MDA) as a marker of oxidative stress was e...
BACKGROUND Tea and coffee are the most commonly consumed beverages in the worldwide. The relationship between tea and coffee consumption on the risk of laryngeal cancer was still unclear. METHODS Relevant studies were identified by searching electronic database (Medline and EMBASE) and reviewing the reference lists of relevant articles until Oct. 2013. Observational studies that reported RRs ...
AIM AND OBJECTIVE Laryngeal carcinoma is one of the most aggressive cancers of the head and neck region. The survival rate of patients with laryngeal carcinoma is low due to its late metastases and resistance to chemotherapy and radiotherapy. It was reported that mTOR was involved in the growth and apoptosis of various cancer cells. The aim of this study was to detect the effects of mTOR inhibi...
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