We compared the efficacy of nebulized (N) and sprayed (S) topical anaesthesia prior to fibreoptic bronchoscopy in a blinded study involving 54 patients aged 57 +/- 26 yrs (mean +/- SD). Cough frequency, recorded on cassette tape, was the index of efficacy. All patients received 100 mg lignocaine sprayed into the pharynx, or nebulized in random order prior to bronchoscopy, and all received intra...

I agree that lignocaine is not a reliable alternative to a beta blocker in the management of adrenergically induced disturbances (Scott, Davie and Stephen, 1971). Lignocaine is a cell membrane stabilizer with a special affinity for neuromuscular tissue and is effective when given intravenously in relatively enormous doses. Like propanidid it may inactivate the baroreceptor mechanism to cause re...

Introduction: This randomized comparative study was planned to compare intracuff alkalinized lignocaine versus dexamethasone in preventing postoperative laryngotracheal morbidity. During general anesthesia patients were intubated with cuffed endotracheal tubes provide effective positive pressure ventilation as well prevent risk of aspiration. The cuffs inflated air. air these can cause signific...

Objective: To compare the effectiveness of betamethasone gel and lidocaine application in reduction post-operative sore throat. Study Design: Randomized controlled trial Place Duration: was conducted at anesthesia department Dow University Health Sciences, Karachi with duration from May 2022 to October 2022. Methodology: A total 54 patients were enrolled divided into two groups Betamethasone Li...

background digital nerve block is commonly performed by care providers in medical fields. this study compares the blocks in terms of effectiveness of anesthesia and pain. methods patients were divided into two groups. first group underwent digital block whereas 2nd group had transmetacarpal digital block. the subcutaneous ring block was performed by two injections of 3 ml of 2% lignocaine in a ...

The effects of the cutaneous application of EMLA cream (a eutectic mixture of lignocaine and prilocaine in their base form) were studied in volunteers. When tested by pin-prick, EMLA cream 2.5% and 5% produced analgesia of the area tested, the cream being most effective if left in contact with the skin for 60 min. The pain produced by the insertion of an i.v. cannula was successfully blocked by...

Plasma levels of local anaesthetics following their injection are affected by many factors. Serial plasma levels following injection of lignocaine and prilocaine at various rates in over 500 patients have been measured and this has allowed some of these factors to be assessed and quantified. The vascularity of the site of injection causes major differences in the maximum plasma level. Prilocain...