In tropical regions millions of people still live at risk of malaria infection. Indeed the emergence of resistance to chloroquine and other drugs in use in these areas reinforces the need to implement alternative prophylactic strategies. Genistein is a naturally occurring compound that is widely used as a food supplement and is thought to be effective in countering several pathologies. Results ...

Figure 1: T1ρ dispersion response in different liver pathologies. Fibrotic livers shows a higher dispersion response than normal while a liver with carcinoma shows a lower dispersion response. Figure2: T1ρ map of cirrhotic human liver explants at different spin-lock frequencies. Within the same stage of fibrosis (F4 on the Metavir scale), T1ρ MR imaging is able to distinguish smaller, more subt...

Fibrosis arises as part of a would-healing response that maintains organ structure and integrity following tissue damage but also contributes to a variety of human pathologies such as liver fibrosis. Liver fibrosis is an abnormal response of the liver to persistent injury with the excessive accumulation of collagenous extracellular matrices. Currently there is no effective treatment, and many p...

Objective: to improve diagnostic and therapeutic tactics in patients with cholelithiasis combination NAFLD, taking into account the impact of comorbidity. Materials methods: We examined 180 people who applied Lotos Medical Center Chelyabinsk period 2018-2020 NAFLD at age 19 65 years. The study included 128 women (72%) 52 men (28%). mean participants was 51.3±9 work took anamnestic (comorbid pat...

ampullary tumor is a rare cancer. these patients most commonly present with obstructive jaundice but sometimes disease appear with uncommon signs. this report is an example of such cases. our case is a 53 year old man who presented with recurrent fever and chills and iron deficiency anemia and has been misdiagnosed for two years. the proper diagnosis occurred when the patient showed abnormal li...

: Hepatocellular carcinoma (HCC) is the most prevalent type of primary cancer liver in adults represent about 80%-90% all cancers. It essential to differentiate HCC and intrahepatic cholangiocarcinoma metastatic carcinoma. Arginase-1 was considered as sensitive specific marker benign malignant hepatocyte. This study aimed detect diagnostic role immunohistochemical expression arginase-1 differen...

Gut-derived bacterial lipopolysaccharide (LPS) and subsequent hepatic toll-like receptor 4 (TLR4) activation have been recognized to be involved in the onset of diet-induced nonalcoholic fatty liver disease (NAFLD), but little is known about the variation of LPS and TLR4 during the progression of NAFLD. Probiotics were able to inhibit proliferation of harmful bacteria and improve gastrointestin...

UNLABELLED INTRODUCTION. The inactive hepatitis B surface antigen (HBsAg) carrier state is usually characterized by minimal or absent liver pathology. However, in developing countries, owing to the very early age of infection with hepatitis B virus (HBV), this state is reached after a very prolonged immune tolerant and immune reactive phase, during which considerable liver damage may have occur...