OBJECTIVES Few interventions have been designed that provide standardised information to primary care clinicians about the diagnostic and treatment recommendations resulting from cancer multidisciplinary team (MDT) (tumour board) meetings. This study aimed to develop, implement and evaluate a standardised template for lung cancer MDTs to provide clinical information and treatment recommendation...

INTRODUCTION The inspiratory flow pattern influences CO₂ elimination by affecting the time the tidal volume remains resident in alveoli. This time is expressed in terms of mean distribution time (MDT), which is the time available for distribution and diffusion of inspired tidal gas within resident alveolar gas. In healthy and sick pigs, abrupt cessation of inspiratory flow (that is, high end-in...

OBJECTIVE To compare the occurrence, duration and severity of ENL in leprosy patients treated with either 12 or 24 months of standard multi-drug therapy (MDT). MATERIALS AND METHODS STUDY POPULATION 296 patients treated with MDT for 2 years, between 1985 and 1992 and followed up as part of a relapse study; and 293 patients, treated between 1998 and 2004, with MDT for 1 year and also follow...

Reliability and energy efficiency are the crucial issues for construction of Underwater Acoustic Networks (UANs). Many schemes have been developed to improve reliability and energy efficiency in UANs. However, most of the existing schemes are based on the unrealistic assumptions that the noise in the underwater surrounding is uniformly distributed and the attenuation of noise is not considered....

The reactivity of old hypertensive rat aortas has not been investigated in relation to each phenotype of the blood pressure curve, mean arterial pressure (MAP), and pulse pressure (PP). Aortic reactivities from 3- to 78-week-old Wistar-Kyoto rats (WKY) and spontaneously hypertensive rats (SHR) were studied with the use of organ chambers and invasive blood pressure, carotid diameter, and histomo...

Twenty years ago, dapsone resistance had become so widespread a phenomenon among both treated and untreated leprosy patients, that the achievements of leprosy control obtained during the preceding 30 years by large scale dapsone monotherapy were in serious jeopardy. To avert the further spread of dapsone resistance, immediate implementation of multidrug therapy (MDT) was recommended by the WHO ...

OBJECTIVES The objective was to characterise and identify potential risk factors for intolerance to multi-drug leprosy therapy (MDT) which prompted a medication change in a leprosy referral centre in northeastern Brazil. DESIGN A retrospective chart review of leprosy patients treated at a state referral centre for leprosy in Natal, Rio Grande do Norte, Brazil was completed. Chart review focus...

Although the prevalence of leprosy has significantly decreased since the introduction of theWorld Health Organization (WHO) regimen of multidrug therapy (MDT), the incidence remains high, with a report of approximately 215 656 cases globally in 2013. Among these, 126 913 cases were reported from India alone [1]. Of a total number of 3196 relapse cases, India alone contributed 486 cases [1]. For...