Alzheimer’s disease (AD)[1] is a fatal brain disorder and alone in United States approximately 4.5 millions Americans are suffering from this disease which is expected by 2050 to range between 11.3 million to 16 million[2] Alzheimer’s disease is a form of dementia, in which nerve cells in memory areas of brain and eventually other areas begin to die at accelerated rate resulting in serious dete...

Adenylyl Cyclase 3 (AC3) plays an important role in the olfactory sensation-signaling pathway in mice. AC3 deficiency leads to defects in olfaction. However, it is still unknown whether AC3 deficiency affects gene expression or olfactory signal transduction pathways within the main olfactory epithelium (MOE). In this study, gene microarrays were used to screen differentially expressed genes in ...

Massive ovarian edema (MOE) is a rare benign clinical entity that can be confused with neoplastic ovarian tumor. Usually, ovarian torsion develops secondary to an ovarian tumor, but at times, it might develop even in a normal ovary. Most MOE occurs because of intermittent torsion of the normal ovary and compromised venous or lymphatic drainage, which subsequently involve the arteries. The major...

Differences in sensitivity of monkeys and humans to antisense oligonucleotide (ASO)-induced complement alternative pathway (AP) activation were evaluated in monkeys, humans, and in serum using biochemical assays. Transient AP activation was evident in monkeys at higher doses of two 2'-O-methoxyethyl (2'-MOE) ASOs (ISIS 426115 and ISIS 183750). No evidence of AP activation was observed in humans...

1 Integrated Transport Research Center of China, Beijing Jiaotong University, No. 3 Shangyuancun, Haidian District, Beijing 100044, China 2 MOE Key Laboratory for Urban Transportation Complex Systems Theory and Technology, Beijing Jiaotong University, No. 3 Shangyuancun, Haidian District, Beijing 100044, China 3 School of Economics and Management, Chang’an University, Nan Er Huan Zhong Duan, Xi...

Sparsely Mixture of Experts (MoE) has received great interest due to its promising scaling capability with affordable computational overhead. MoE models convert dense layers into sparse experts, and utilize a gated routing network make experts conditionally activated. However, as the number grows, outrageous parameters suffers from overfitting data allocation. Such problems are especially sever...

In real life, either the subjective factors of speakers or objective environment degrades performance automatic speech recognition (ASR). This study focuses on one factors, accented speech, and attempts to build a multi-accent ASR system solve degradation caused by different accents, whose characteristic is low resource. To deal with challenge low-resource data styles, wav2vec-MoE (mixture expe...

Finding alternative to most well known classical family of distributions has become a topic of high importance in academic research due to their striking properties. An increasing interest can be observed for the art of adding parameter to some existing distributions as one parameter family of distributions is not sufficient to handle various real contexts. There is a vast amount of literature ...

Xuezhe Ma, Xiaotian Zhang, Hai Zhao, Bao-Liang Lu Center for Brain-Like Computing and Machine Intelligence Department of Computer Science and Engineering, Shanghai Jiao Tong University MOE-Microsoft Key Laboratory for Intelligent Computing and Intelligent Systems Shanghai Jiao Tong University, 800 Dong Chuan Rd., Shanghai 200240, China {xuezhe.ma,xtian.zh}@gmail.com, {zhaohai,blu}@cs.sjtu.edu.c...

a Department of Physics and Astronomy, University of Iowa, Iowa City, IA 52240, USA b Key Laboratory of Quark & Lepton Physics (MOE) and Institute of Particle Physics, Central China Normal University, Wuhan, 430079, China c Fakultät für Physik, Universität Bielefeld, D-33615 Bielefeld, Germany d Physics Department, Brookhaven National Laboratory, Upton, NY 11973, USA e Center for Computational ...