A patient residing in New Mexico had murine typhus diagnosed. A novel molecular assay was performed at the Centers for Disease Control and Prevention, and Rickettsia prowazekii, the agent of epidemic typhus, was found, rather than R. typhi. To our knowledge, this is the first reported case of epidemic typhus confirmed by means of polymerase chain reaction--based testing of cerebrospinal fluid, ...

State Key Laboratory of Analytical Chem Innovation Center of Chemistry for Life Scie Engineering, Nanjing University, Nanjing 21 cn; [email protected] Key Laboratory of Nuclear Medicine, Minis Molecular Nuclear Medicine, Jiangsu Instit 214063, China † Electronic supplementary information (E qRT-PCR assay, western blot assay, feas assay, and specic measurement of RISC. Cite this: Chem. Sci., 2017...

A radioimmunoprecipitation method has been devised which permits the direct identification of those proteins which are both exposed on the cell surface of Haemophilus influenzae type b and accessible to antibody. Both extrinsically and intrinsically radiolabeled cells of this organism were employed as the sources of antigen in radioimmunoprecipitation experiments which involved incubation of in...

MEASURED BY THE ALICE FAR-ULTRAVIOLET SPECTROGRAPH ON ROSETTA. B. A. Keeney1, S. A. Stern1, M. F. A’Hearn2, J.-L. Bertaux3, L. M. Feaga2, P. D. Feldman4, J. Wm. Parker1, E. Schindhelm1, A. J. Steffl1, M. Versteeg5, and H. A. Weaver6 1Southwest Research Institute, Department of Space Studies, Boulder, CO 80302, USA, [email protected], 2Department of Astronomy, University of Maryland, College Par...

Aims: The membrane associated tyrosinase is an enzymatically active monomeric glycoprotein which purified to only a low degree. It has gained importance in the present era due its antioxidant and immunomodulatory properties as well applications industry. Moreover role synthesis of melanin skin for protection from UV radiations also paved way towards better understanding this enzyme.
 Study...

We evaluated the new, fully automated molecular BD Max methicillin-resistant Staphylococcus aureus (MRSA) assay for detection of methicillin-resistant S. aureus in a low-prevalence (4.1%) setting. Sensitivity, specificity, and positive and negative predictive values were 93.9%, 99.2%, 83.8%, and 99.7%, respectively. The assay reported fewer unresolved results than the BD GeneOhm MRSA ACP assay.

Introduction: Profilin1 (PFN1) is a ubiquitously expressed protein known for its function as a regulator of actin polymerization and dynamics. A recent discovery linked mutant PFN1 to Amyotrophic Lateral Sclerosis (ALS), which is a fatal and progressive motor neuron disease. We have also demonstrated that Gly118Val mutation in PFN1 is a cause of ALS, and the formation of aggregates containing m...

Ornithobacterium rhinotracheale (ORT) is a bacterium associated with respiratory disease, growth retardation, decreased egg production and mortality in chickens and turkeys. The objective of this study was isolation, identification and evaluation of antimicrobial susceptibility of ORT bacterium in slaughtered broilers chicken flocks based on cultural and molecular tests in Khuzestan pr...