multiple sclerosis (ms) is an autoimmune disease of central nervous system. since different types of immune cells are involved in ms pathogenesis, in this study we aimed to evaluate serum levels of several immunological components including soluble cd4 (scd4), scd8, scd163, and immunoglobulins as markers of activity of t-cells, macrophages, and b-cells in different types of ms. serum levels of ...

The aim of this paper is to develop a rapid, and highly sensitive quantitative HPLC fingerprint method with multiple indicators by using the Compound Chinese Medicine Wuwei Changyanning granule and 5 herbs in the prescription. The quantitative fingerprint chromatogram with multiple indicators was investigated. ⅰ)6 compositions included rutin, gallic acid, chlorogenic acid, atractylenolideⅠ, pac...

there are many real problems in which multiple responses should be optimized simultaneously by setting of process variables. one of the common approaches for optimization of multi-response problems is desirability function. in most real cases, there is a correlation structure between responses so ignoring the correlation may lead to mistake results. hence, in this paper a robust approach based ...

extramedullary plasmacytoma (emp) is a rare neoplasm of soft tissue which usually arises in the respiratory tract, nasal cavity, sinuses and nasopharynx. multiple extramedullary plasmacytomas are extremely rare, especially those that are not associated with multiple myeloma.we describe multiple primary emp in a 37 year old man, without involvement of bone or bone marrow. emp usually has a good ...

background in stable patients with blunt abdominal trauma, accurate diagnosis of visceral injuries is crucial. objectives to determine whether repeating ultrasound exam will increase the sensitivity of focused abdominal sonography for trauma (fast) through revealing additional free intraperitoneal fluid in patients with blunt abdominal trauma. patients and methods we performed a prospective obs...

multiple sclerosis (ms) is a chronic inflammatory disease of the central nervous system characterized by widespread inflammation, focal demyelination and a variable degree of axonal and neuronal loss. ionic conductances regulate t cell activation as well as neuronal function and thus have been found to play a crucial role in ms pathogenesis. since present therapeutical approaches are only parti...

multiple sclerosis is an autoimmune cns-disease characterized by inflammatory neurodegenerative events occurring with de- and remyelination. recent evidence show that demyelinated neurons are less excitable than myelinated ones while at early stages of remyelination these neurons seem to be hyperexcitable. the latter is a transitory condition that, very likely, leads to impaired neuronal networ...

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