Immune regulation of autoimmune disease can function at two sites: at the secondary lymphoid organs or in the target organ itself. In this study, we investigated the natural resolution of autoimmune pathology within the CNS using murine experimental autoimmune encephalomyelitis (EAE). Recovery correlates with the accumulation of IL-10-producing CD4+CD25+ T cells within the CNS. These CD4+CD25+ ...

Intense motivational salience attribution is considered to have a major role in the development of different psychopathologies. Numerous brain areas are involved in "normal" motivational salience attribution processes; however, it is not clear whether common or different neural mechanisms also underlie intense motivational salience attribution. To elucidate this a brain area and a neural system...

Studies of a mouse model of genetic resistance to herpes simplex virus type 1 (HSV-1) indicate that the marrow-dependent effector cell of allogeneic resistance plays an important role in natural resistance to this virus infection. Since the marrow-dependent effector cell appears to be closely related to the natural killer (NK) cells, an NK assay with HSV-1-infected fibroblasts [NK(HSV-1)] has b...

Trade and Migration with Renewable Natural Resources: Out-of-Steady-State Dynamics Commodity price increases associated with the entry of China, India and other countries into the world economy has led to increased pressure on common-property renewable natural resources (NR). The problem is particularly worrisome for economies that obtain a large share of their income from the exploitation of N...

The aim of this research was to investigate the environmental impacts of olive fruit production under different orchard size and upon organic and common agro-systems through Life Cycle Assessment (LCA) methodology in Rudbar region, Guilan province, northern Iran. The data were collected using a self-structured questionnaire and face-to-face interview with 305 olive growers in the study region. ...

A phenomenological method based on the natural orbital representation is applied to construct the ground state one-body density matrix which describes correctly both density and momentum distributions in He, O and Ca nuclei. The parameters of the matrix are fixed by a best fit to the experimental density distribution and to the correlated nucleon momentum distribution. The method allows the nat...

The concept of ‘genuine’ saving, the net saving rate in a national accounting framework encompassing resource depletion and environmental degradation, is extended to include technological change, resource imports, and critical natural capital in the form of rainforests. In all cases, measuring negative rates of genuine saving on the optimal path implies non-sustainability of the path. Questions...

Research on executive functioning and on self-regulation have each identified a critical resource that is central to that domain and is susceptible to depletion. In addition, studies have shown that self-regulation tasks and executive-functioning tasks interact with each other, suggesting that they may share resources. Other research has focused specifically on restoring what we propose is the ...

This note offers a general proof of the converse of Hartwick’s rule, namely that — in an economy with stationary instantaneous preferences and a stationary technology — an efficient constant utility path is characterized by the value of net investments being zero at each point in time. In a one consumption economy with two stocks — a stock of a natural resource and a stock of man-made capital —...