BACKGROUND Oral lichen Planus (OLP) is a chronic inflammatory disease involving skin and mucous membranes. Its etiology is still uncertain whilst an autoimmune mechanism is known to be implicated. OLP is commonly considered a geriatric disease and gender differences in prevalence are clear, whereby females are generally more frequently affected than males more often during the 5th and 6th decad...

Oral lichen planus (OLP) is a chronic inflammatory disease with different clinical types. Reticular and erosive forms are the most common. Although the cause of OLP remains speculative, many findings suggest auto-immune involvement, mediated by T lymphocytes against the basal keratinocytes. Inflammation, mechanical trauma or toxic agents can affect the epithelial homeostasia. Increased apoptosi...

Oral lichen planus (OLP) is a T-cell mediated disease directed to a still unknown antigen, which may affect oral mucosa. The aim of this study was to determine whether differences in anxiety, depression and stress could be seen in patients with OLP in acute stage and in remission, as well as in comparison with healthy control subjects. The study included 50 OLP patients aged 22-79 (mean age 61....

Oral lichen Planus(OLP) is a chronic mucocutaneous autoimmune disease that mostly affects middle-aged females. Various factors including psychological stress , drugs and various systemic conditions has been linked to the etiopathogenesis of OLP. It has got several variants including reticular, erosive, atrophic and ulcerative-types. Erosive and atrophic variants have been most often linked to i...

Genomics has promised to change the practice of dentistry. Since the complete sequencing of the Human Genome, the development of massscale research tools in this field, such as DNA microarrays, has greatly improved [1]. Recent studies have employed microarray technology to monitor gene expression in periodontal patients, strain diversity of oral microflora implied in periodontitis, and the effe...

: Oral lichen planus (OLP), a chronic inflammatory mucocutaneous disorder varying in appearance, affects the mucus membrane of oral cavity and is potentially premalignant. Various therapeutic regimens have been developed for management OLP highlighting steroids as first-line procedure. Recently, modalities like lasers, photodynamic therapy (PDT), photobiomodulation (PBM) has also mentioned lite...

background and aims. lichen planus is a chronic inflammatory disorder with unspecified etiology, appearing as a result of stress, genetic predisposition and immunologic factors. erosive type of the disease is more important because of its clinical symptoms of pain, irritation and malignancy risk. despite various medications used, a definite cure for lichen planus is unknown. regarding the effec...

Aim of the present investigation was to analyse the possible malignant transformation of oral lichen planus to carcinoma, especially in the atrophic erosive forms and those displaying plaques involving the top of the tongue. A review has been made of the literature, from 1986 to the present day. This search outlines the relationship between oral lichen planus, hepatitis C virus infection, Epste...

STATEMENT OF THE PROBLEM Oral Lichen planus (OLP) is an autoimmune mucocutaneous disease. There are some reports of thyroid diseases, especially hypothyroidism, to have association with OLP in some studies. PURPOSE Based on the controversial results of former studies in other populations about the association of hypothyroidism and OLP, the current study aimed to evaluate this association in a...