Oral melanoma is a rare aggressive neoplasm which accounts for only 0.2-8% of all reported malignant melanomas. The common sites of its occurrence are the palate and gingiva with the maxillary arch being affected 80% of the time. Because of their presence at relatively obscure areas in the oral cavity, most of the malignant melanomas of the oral cavity are diagnosed at a late stage. We report a...

Sir, We read with interest the letter from Thestrup-Pedersen & Søndergaard (1) reporting the augmentation of len-tiges and naevi in a young male patient who had been self-injecting with " melanotan ". As in a case we initially reported (2), a clinically suspicious naevus was excised, with histology revealing a benign naevus, with no evidence of malignant transformation. The patient was also not...

BACKGROUND To analyze the presence of salivary Epstein-Barr virus (EBV) DNA in oral squamous cell carcinoma and potentially malignant oral disorders. MATERIAL AND METHODS Three groups were studied: Group 1 (12 oral squamous cell carcinomas (OSCC)), Group 2 (12 potentially malignant oral disorders (PMD)) and Group 3 (47 healthy controls). EBV DNA salivary analysis was performed by PCR. RESUL...

BACKGROUND Malignant mesothelioma (MM) is almost always fatal and few treatment options are available. The aim of this study was to evaluate the efficacy of oral cyclophosphamide and etoposide for patients who underwent standard treatment for advanced MM. MATERIALS AND METHODS This study included 22 malignant pleural mesothelioma patients who were treated with oral cyclophosphamide and etopos...

INCIDENCE AND BIOLOGIC BEHAVIOR OF ORAL TUMORS Malignant tumors of the oral cavity are the fourth most common of all cancer types in the dog and cat, representing 5.4% of all malignant neoplasms. The annual incidence rate in dogs and cats in one study was 20.4 and 45.43 cases per 100,000, respectively. Cocker spaniels, poodles, German shepherds, German shorthaired pointers, weimaraners, golden ...

Many malignant tumours other than squamous cell carcinoma may present in the oral cavity. Melanomas of the oral cavity are usually pigmented, aggressive tumours associated with a poor prognosis. Neoplasms of the minor salivary glands have a greater tendency to be malignant than those of the major glands, and some exhibit a predilection for occurring in the mouth. Many types of connective tissue...

Aim of the present investigation was to analyse the possible malignant transformation of oral lichen planus to carcinoma, especially in the atrophic erosive forms and those displaying plaques involving the top of the tongue. A review has been made of the literature, from 1986 to the present day. This search outlines the relationship between oral lichen planus, hepatitis C virus infection, Epste...

BACKGROUND Oral cancer is associated initially by the presence of pre-malignant lesions or pre-malignant conditions. Oral Leukoplakia is one of the best-known pre-malignant lesions in the oral cavity that have the highest rate of malignant transformation. Numerous studies have shown an altered lipid profile in various cancers including head and neck cancers. An inverse relationship between plas...