introduction: lower level of estrogen hormone is considered as an important factor for loss of learning and memory in postmenopausal women. although estrogen replacement therapy is used for compensation, but long-term usage of estrogen is associated with a higher risk of hormonedependent cancers. phytoestrogens, due to fewer side effects, have been proposed to prevent menopause-related cognitiv...

introduction: the role of ovarian hormones and nitric oxide (no) on oxidative damage in brain tissues as well as learning and memory has been widely investigated.the present study was carried out to evaluate the effect of the precursor of no, l-arginine on learning and brain damage due to oxidative stress in ovariectomized (ovx) rats.methods: thirty -two rats were divided into four groups: 1) s...

Background. A higher prevalence of cardiovascular disorders has been observed in women after menopause. This study aimed to determine the long-term effects ovariectomy on hemodynamic functions and level nitric oxide metabolites (NOx) heart tissue ovariectomized rats. Methods. Fourteen female Wistar rats were divided into two groups (n=7 each group) control (OVX). OVX rat model was induced using...

Milletia aboensis has long-standing ethnopharmacological indications for the treatment of symptoms and diseases related to menopause. This investigation examined effects its phytoestrogen-rich fraction on some predictors cardiovascular risk in an ovariectomized rat model In vitro, antioxidant activity was determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) test. Ovariectomy used trigger menop...

Objective(s): The beneficial and more potent role of exercise to prevent heart apoptosis in ovariectomized rats has been known. The aim of this study was to examine the effects of swimming training on cardiac expression of Bcl-2, and Mir-133 levels and glycogen changes in the myocyte. Materials and Methods: Forty animals were separated into four groups as control, sham, ovariectomy (OVX) and o...

Background Cardiovascular events are less prevalent in premenopausal women and women receiving estrogen replacement than in postmenopausal women or men. Endotheliumderived relaxing factor (EDRF) is an important local modulator of vascular tone, and abnormal endothelial function is related, in part, to the oxidative modification of low-density lipoprotein (LDL). Estrogens possess substantial ant...

A study was conducted to determine whether compensatory ovarian hypertrophy occurred in prepuberal heifers, and if so, could compensatory ovarian hypertrophy be prevented by injecting charcoal-extracted bovine follicular fluid (CFF). An additional objective was to determine the effect of CFF injections on follicle stimulating hormone (FSH) and luteinizing hormone (LH) concentrations following u...

Endogenous sex hormones seem to influence the risk of several common and debilitating diseases. With a view toward better understanding the effects of surgical removal of the ovaries and high-dose pelvic radiotherapy on plasma sex hormone levels, we measured estrogen and androgen concentrations cross-sectionally among 147 women who had been treated for cervical cancer 0.3-18.5 years previously....