Chemoselective oxime coupling was used for facile conjugation of unprotected, reducing glycans and glycopeptide aldehydes with core?shell gold nanoparticles carrying reactive aminooxy groups on the organic shell.

Eye exposure to the extremely toxic organophosphorus sarin results in long-term miosis and visual impairment. As current treatment using atropine or homatropine eye drops may lead to considerable visual side effects, alternative combined treatments of intramuscular (im) oximes (16.8 µmol/kg, im) with atropine (0.5 mg/kg, im) or with the short acting antimuscarinic tropicamide (0.5%; w/v) eye dr...

Oxime extractants 3-tert-butyl-2-hydroxy-5-methyl benzaldehyde oxime (HL1) and 3-tert-butyl-2-hydroxy-5-methoxy benzaldehyde oxime (HL2) were synthesized and characterized by conventional spectroscopic methods. Suitable lipophilic nature of the prepared extractants allowed examining the ability of these molecules for extr...