the present study investigates the possibility of enriching adult artemia franciscana with singular or combined administration of pediococcus acidilactici and fructooligosaccharide (fos). the experiment was conducted in a completely randomized design with four treatments, including synbiotic, p. acidilactici +fos (t1), probiotic, p. acidilactici (t2), prebiotic, fos (t3) and control (t4). to ev...

Adaptation to hypoxia is mediated through a coordinated transcriptional response driven largely by hypoxia-inducible factor 1 (HIF-1). We used ChIP-chip and gene expression profiling to identify direct targets of HIF-1 transactivation on a genome-wide scale. Several hundred direct HIF-1 targets were identified and, as expected, were highly enriched for proteins that facilitate metabolic adaptat...

An overview of the radiation damage induced problems connected with the application of silicon particle detectors in future high-energy physics experiments is given. The present knowledge on the deterioration of the detector performance caused by irradiation with neutrons and high energetic protons is described leading to an appropriate modeling of the macroscopic parameters under irradiation, ...

Disrupted iron metabolism has been implicated in the pathogenesis of Parkinson's disease (PD), a progressive neurodegenerative disorder that severely affects movement and coordination, yet the molecular mechanisms underlying this association remain unknown. To this end, we performed a transcriptomic meta-analysis of four blood microarrays in PD. We observed a significant downregulation of genes...

Context. We present the physical and chemical properties of intermediate-mass stars models of low metallicity, evolved along the thermal pulse phase. Aims. The target of this work is to extend to low metallicities, Z=1,2 and 6 × 10, the models previously computed for chemistries typical of Globular Clusters of an intermediate metallicity (Z=0.001), and for the most metal-rich clusters found in ...

One membrane oxygen enricher (Oxygen Enrichment Company OE-4E) and four molecular sieve (MS) concentrators (Mountain Medical Econo2, De Vilbiss MINI DeVO2, Cryogenic Roomate III, and Mountain Medical Mini O2) have been studied to assess technical and clinical performance. During four weeks of continuous operation at a flow rate of 2 l min-1 (6 l min-1 for OE-4E) consistent oxygen levels were de...

It is widely accepted that the oxygen produced by photosystem II of cyanobacteria, algae, and plants is derived from water. Earlier proposals that bicarbonate may serve as substrate or catalytic intermediate are almost forgotten, though not rigorously disproved. These latter proposals imply that CO2 is an intermediate product of oxygen production in addition to O2. In this work, we investigated...

We present long slit optical spectroscopy of 67 H II regions in 21 dwarf irregular galaxies to investigate the enrichment of oxygen, nitrogen, neon, sulfur, and argon in low mass galaxies. Oxygen abundances are obtained via direct detection of the temperature sensitive emission lines for 25 H II regions; for the remainder of the sample, oxygen abundances are estimated from strong line calibrati...

Recently, hypoxia has become serious in Lake Biwa due to progressing of global warming. In this study, we determined Mn and As concentrations and their speciation in lake bottom water and sediments in June and December to elucidate their geochemical behaviors. Lake bottom water and sediment samples were collected from seven stations in the northern basin of Lake Biwa. In sediments, clear enrich...

Bacterial abundance and production (thymidine and leucine incorporation) were measured along a salinity gradient from the Mississippi Rlver (0 % o ) to the open waters of the Gulf of Mexico (36 %a) during July-August 1990 and February 1991. Bactenal production in surface waters was maximal at intermediate salinities (15 to 30 %o). Nutrlent enrichment experiments suggested that bacterial growth ...