A new nano-sized lead(II) coordination polymer, [Pb(2bpdh)(NO3)2]n(1); (2-bpdh = 2,5-bis(2-pyridyl)-3,4-diaza-2,4hexadiene)}, was synthesized by a sonochemical method. The structure of 1 may be considered coordination polymer of lead(II) consist of metallocyclicchains formed by bridging NO3 and 2-bpdh ligands. The thermal stability of compound was studied by thermal gravimetric and differential...

SAT solvers have proved to be very efficient in verifying the correctness of automotive product documentations. However, in many applications a car configuration has to be optimized with respect to a given objective function prioritizing the selectable product components. Typical applications include the generation of predictive configurations for production planning and the reconfiguration of ...

trasal-contact method test using glass petri-dish rather than the conventional glass jar was used to evaluate the permethrin toxicity and synergism effect of piperonal butoxode (pbo) on nymphae of five strains of blattella germanica (l.). the test was carried out on 2-3 days old of first nympal stage, at four replicates of 10 cockroaches. the susceptible strain showed t50 and kt50 of 12.81 and ...

Background: Lemborexant (LEM), a dual-orexin-receptor-antagonist approved to treat adults with insomnia, increases total sleep time (TST) and rapid eye movement (REM) sleep. Patients obstructive apnea (OSA) or co-morbid insomnia OSA (COMISA) report sleeping difficulties reduced REM, therefore architecture was analyzed during LEM treatment. Methods: Study E2006-G000-304 (NCT02783729) 1-month, ra...

A new nano-sized lead(II) coordination polymer, [Pb(2-bpdh)(NO3)2]n (1); (2-bpdh = 2,5-bis(2-pyridyl)-3,4-diaza-2,4-hexadiene)}, was synthesized by a sonochemical method. The structure of 1 may be considered coordination polymer of lead(II) consist of metallocyclicchains formed by bridging NO3- and 2-bpdh l...

Abstract Background Upadacitinib (UPA), an oral, selective JAK inhibitor demonstrated superior efficacy for clinical remission compared with placebo (PBO) and acceptable safety profile in patients moderately to severely active Crohn’s disease (CD) 2 phase 3 induction trials, U-EXCEL (NCT03345849) U-EXCEED (NCT03345836).1-2 There remains unmet need therapies that provide rapid symptom relief amb...

Haplotype inference from genotype data is a key computational problem in bioinformatics, since retrieving directly haplotype information from DNA samples is not feasible using existing technology. One of the methods for solving this problem uses the pure parsimony criterion, an approach known as Haplotype Inference by Pure Parsimony (HIPP). Initial work in this area was based on a number of dif...

OBJECTIVE The aim of this study was to study valproate efficacy and safety for aggression in children and adolescents with pervasive developmental disorders (PDD). METHODS In this prospective double-blind, placebo-controlled study, 30 subjects (20 boys, 10 girls) 6-20 years of age with PDD and significant aggression were randomized and received treatment with valproate (VPA) or placebo (PBO) ...