Angiogenin (ANG), originally identified as an angiogenic ribonuclease, has recently been shown to play a direct role in prostate cancer cell proliferation by mediating rRNA transcription. ANG is up-regulated in human prostate cancer and is the most significantly up-regulated gene in AKT-driven prostate intraepithelial neoplasia (PIN) in mice. Enhanced cell proliferation in the PIN lesions requi...

Auxin is a key regulator of plant development and its differential distribution in plant tissues, established by a polar cell to cell transport, can trigger a wide range of developmental processes. A few members of the two families of auxin efflux transport proteins, PIN-formed (PIN) and P-glycoprotein (ABCB/PGP), have so far been characterized in maize. Nine new Zea mays auxin efflux carriers ...

This article explores the management of skeletal pin sites focusing on the research that underpins current practice. The effectiveness of pin site care depends on assessment and delivery of appropriate care. Because pin site management varies greatly between clinical areas, it is important that clinicians are aware of the evidence base on which their current practice is founded.

A numerical finite difference study has been earned out for two dimensional radiation-natural convection interaction phenomena in a vertical circular pin located at a non-participating (i.e. transparent) fluid. The coupled conservation equations in boundary layer (continuity, momentum, and energy equations) and pin energy equation are solved simultaneously using modified box method and fully im...