background and objectives: the expanding field of psychopharmacology is constantly seeking new and improved drugs to treat psychiatric disorders. although psychotropic drugs have had a remarkable impact in psychiatry, their utilization, effectiveness, and side effects in the in clinical practice need continuous study. the present study was thus designed to analyze the pattern of psychotropic dr...

drug utilization evaluation (due) is an effective program to identify variability in drug use and to support interventions that will improve patient outcomes. the appropriate use of enoxaparin, a low molecular weight heparin (lmwh), which is widely used as curative or preventive treatment of thromboembolic disorders was assessed in the study. a prospective due was carried out at masih daneshvar...

This paper analyzes the impact of uncertainty concerning product quality of generic drugs on the substitution behavior of prescribing physicians. It is shown that uncertainty about the generic drug quality gives the physician a value of waiting for more information before switching to the generic version. In addition, it is shown that reducing the approval requirements for generic drugs, thereb...

We discuss, in this paper, the dynamical properties of extremely diluted, non-monotonic neural networks. Assuming parallel updating and the Hebb prescription for the synaptic connections, a flow equation for the macroscopic overlap is derived. A rich dynamical phase diagram, was obtained, showing a stable retrieval phase, as well as a cycle two and chaotic behavior. Numerical simulations were p...

BACKGROUND 23 million Americans suffer from migraine headaches, incurring more than $1 billion in direct medical costs each year (with another $13 billion in indirect productivity losses). Triptans are the most common treatment of choice for these patients; however, adherence and persistence to triptans are poor. Partly due to poor adherence to therapy, the ability of triptans to reduce the uti...

BACKGROUND As demonstrated in several publications, low positive predictive value alerts in computerized physician order entry (CPOE) induce fatigue and may interrupt physicians unnecessarily during prescription of medication. Although it is difficult to increase the consideration of medical alerts by physician through an improvement of their predictive value, another approach consists to act o...

Aim: This study was aimed at finding the occurrence rate of prescription errors in the outpatients' prescriptions written by faculty and non-faculty physicians practicing in Shiraz, Iran. Method: In this cross-sectional study 2000 outpatient prescriptions were randomly collected from pharmacies affiliated with Shiraz University of Medical Sciences (SUMS) and social security insurance in Shiraz,...