Location-based Services (LBS) [1] have already started their market penetration process and several platforms capable of running LBS are available. With the number of LBS increasing, the current development is targeting consumer applications, although LBS have a high potential for enhancing business processes in companies as well. Considering business process optimization, one concept recently ...

objective: crispr/cas9 technology provides a powerful tool for targeted modification of genomes. in this system, a donor dna harboring two flanking homology arms is mostly used for targeted insertion of long exogenous dna. here, we introduced an alternative design for the donor dna by incorporation of a single short homology arm into a circular plasmid. materials and methods: in this experiment...

Intracellular membrane trafficking requires correct and specific localization of Rab GTPases. The hypervariable C-terminal domain (HVD) of Rabs is posttranslationally modified by isoprenyl moieties that enable membrane association. A model asserting HVD-directed targeting has been contested in previous studies, but the role of the Rab HVD and the mechanism of Rab membrane targeting remain elusi...

Aim of the article. The purpose article is to substantiate scientific, methodological and practical provisions for use omnichannel marketing tools in political sphere. Achieving goal work necessitated solution following tasks: analyze evolution modern market conditions; determine content complex sphere; investigate effectiveness research study feasibility applying communication policy electoral...