Ferulago W. Koch. (Apiaceae) genus is represented by approximately 50 taxa throughout the world. Ferulago species are known as “Çakşır” or “Çağşır” in Turkey and mostly known for their aphrodisiac effects. However recent reports emphasize the activity of various Ferulago species against cancer, as well. The aim of this study was to investigate the effect of lyophilized extract of F. mughlea Peş...

Craniofacial skeletal metastasis is a rare presentation of advanced prostate cancer. This is a report of a 69-year-old man who presented with numbness of the right lower lip and recently ill-fitting lower denture. Based on the medical history of benign prostate hyperplasia (BPH) and suspicion of a metastatic tumor, prostate core needle biopsy was performed. Histology of the prostate biopsy con...

Prostate cancer is a devastating disease for which current therapies are inadequate. Various lines of evidences have suggested the 5-lipoxygenase (5-LOX) pathway and the leukotriene receptor pathway are potential targets for prevention or treatment of Prostate cancer. Thus, search for new anti-cancer drugs targeting 5-LOX and leukotriene is very essential and important. The objective of the pre...

Objective(s): We performed a phase IIa clinical trial of trans-1-amino-3-18Ffluoro-cyclobutane carboxylic acid (anti-18F-FACBC), a synthetic amino acid analog for PET, in patients with metastatic prostate cancer. Methods: The study subjects consisted of 10 untreated prostate cancer patients having lymph node and/or bone metastasis. Five patients underwent whole-body PET 5 and 30 min after intra...

Introduction The prostate gland is a small reproductive organ found in men. It consists of 3 zones: central, peripheral and transitional. most common localization cancer elderly men the zone. Prostate one cancers ranks second terms incidence fifth lethality among worldwide. There are many factors that contribute to development We can divide them into two large groups: genetic environmental fact...

Abstract The PSA test is used primarily to screen for prostate cancer. A measures the amount of prostate-specific antigen (PSA) in your blood. a protein produced prostate, small gland that sits below man's bladder. mostly found semen, which also prostate. Small amounts ordinarily circulate can detect high levels may indicate presence However, many other conditions, such as an enlarged or inflam...

Background and objectives: Prostate cancer is the second leading cause of mortality among men worldwide, and the eighth cancer-related cause of death in Iran. Male sex hormones (androgens) are the main cause of prostate cancer cells. Triptorelin is considered a synthetic decapeptide analogue of gonadotropin-releasing hormone (GnRH) in the treatment of prostate cancer. This study aimed to evalua...

lymph node (ln) metastasis is considered an important prognostic factor in patients with prostate cancer. the aim of this study was to determine the rate of ln metastasis among an iranian population who underwent radical prostatectomy (rp) with pelvic ln dissection (plnd). in a retrospective review of medical records, 450 rp cases were included and the data on ln metastasis were extracted from ...