This paper presents an approach for simulation of mixedsignal CMOS integrated circuits, aiming at estimating crosstalk effects, by identifying possible sources of disturbances in analog-digital integrated systems, such as current pulses drawn from voltage supplies. A simple expression of voltage and current in the pull-up and the pull-down of a CMOS logic gate can be derived. A computer program...

This paper presents a novel image enhancement algorithm using a multilevel windowed inverse sigmoid (MWIS) function for rendering images captured under extremely non uniform lighting conditions. MWIS based image enhancement is a combination of three processes viz. adaptive intensity enhancement, contrast enhancement and color restoration. Adaptive intensity enhancement uses the non linear trans...

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65 2.1 Material and Methods 66 2.1.1 Plasmid and cloning 66 2.1.2 Cell culture and transfection 66 2.1.3 Assessment of cell viability 67 2.1.4 Assessment of Neurite process length and branching point. 68 2.1.5 Ras Pull-Down Assay 68 2.1.6 Generation of Human LRRK2 Transgenic Flies. 69 2.1.7 Western Blot Analysis. 70 2.1.8 Immunoprecipitation. 71 2.1.9 Optical Neutralization Technique. 71 2.1.10...

End users run GEANT4 executable les customized and provided by application programmers. GAG (GEANT4 Adaptive GUI) is a GUI for them to run GEANT4 by using commands and by changing associated parameters. We have two implementations of GAG, that is, Tcl/Tk and Java versions. GAG provides them with a tree (Java) or Pull-down menu (Tcl/Tk) of commands, a widget of parameter inputs of variable forma...

We report the identification of Ima, a novel Drosophila MAGUK-like protein, which contains two WW and four PDZ protein interaction domains and interacts with the small GTPase dRal in the yeast two-hybrid system and pull-down assays. The gene is expressed in distinct spatiotemporal patterns throughout embryonic development. Overexpression of Ima interferes with normal Drosophila development, ind...

Small ORF (sORF)-encoded small proteins have been overlooked for a long time due to challenges in prediction and distinguishing between coding- noncoding-predicted sORFs their biochemical detection characterization. We report on the first functional characterization of protein (sP26) archaeal model organism Methanosarcina mazei, comprising 23 amino acids. The corresponding encoding leaderless m...

In this paper, we propose four wide domino circuits to improve the robustness and reduce the power consumption. All proposed circuits use small potential at the source of the pull down network in the standby mode. Simulation is done using 90nm HSPICE for 32 input OR gate. Our proposed circuits reduce power consumption by 11.75% to 41.85%, improvement of unity noise gain by 41.03% to 90.87% and ...

Modern Static Random Access Memory (SRAM) systems are susceptible to reliability and variability issues. Examples of reliability and variability issues are Bias Temperature Instability (BTI) in the transistors and resistive/open interconnect defects, respectively. This paper analyzes the impacts of BTI and resistive defects independently as well as simultaneously on the SRAM decoder. First, the...

In order to overcome the loss of performances issue when scaling resonant sensors down to NEMS, it proves extremely useful to study the behavior of resonators up to large displacements and hence high nonlinearities. A comprehensive nonlinear multiphysics model based on the Euler-Bernoulli equation which includes both mechanical and electrostatic nonlinearities in the case of a capacitive doubly...