The origin of soluble CD14 (sCD14) in the circulation is uncertain. To examine whether CD14 could be an acute-phase protein (APP), the levels of sCD14, IL-6, and C-reactive protein were determined by ELISA in serum and synovial fluid (SF) of patients with various arthropathies, and the regulation of CD14 synthesis was examined in liver cells. In patients with crystal-mediated or immunologically...

A 38-year-old man presented with a one-month history of muscle weakness and dysesthesia in the lower extremities, urinary retention, and urinary tract infection after lumbar burst fracture resulted from high fall. During the rehabilitation in our hospital, he had arthritis in both the ankle and knee. However, the patient was treated as gouty arthropathy initially. The arthritis was completely r...

INTRODUCTION This case report describes the effects of psychotropic treatment, quetiapine in particular, on systemic inflammation, pain, general functioning and major depression in the treatment of a woman with arthritis. CASE PRESENTATION A 49-year-old Caucasian Australian woman with arthritis, pain and depression was treated with a course of escitalopram, mirtazapine and quetiapine. Pain le...

Case report We present the case of a 34-year-old female with a medical history of fever lasting 1 week before admission to the County Hospital, Clinic of Diabetes, Nutrition and Metabolic Diseases for multiple-localized arthritis (bilateral tibia-tarsus, left radio-carpal, II and III metacarpus-phalanx right hand, right knee), considered reactive arthritis by the rheumatologist; these symptoms ...

Lymphocyte transformation responses were studied in 21 patients with acute yersinia infection followed-up after the acute infection for up to one year. Eight patients had reactive arthritis caused by yersinia. The responses to the causative serotype of yersinia were significantly lower (p less than 0.05) in patients with arthritis than in those without arthritis. Stimulation with Escherichia co...

The expression of serologic HLA-B27 epitopes on leukocytes of patients with reactive arthritis or ankylosing spondylitis has been shown to be modified in the course of the disease. The purpose of this work was to study whether phagocytosis of arthritis-triggering microbes in vitro alters the expression of HLA-B27 molecules on human antigen-presenting cells and to characterize the underlying mec...

Objective—To assess the eYcacy and safety of sulphasalazine in reactive arthritis. Methods—Double blind placebo controlled trial of six months duration comparing sulphasalazine 2-3 g per day (n = 37) with matching placebo (n = 42) in adults with active reactive arthritis (age 19-57 years, median 34). Treatment response was evaluated once a month by changes in erythrocyte sedimentation rate (ESR...

granulomatosis and hypercalcaemia following intravesical bacillus CalmetteGuérin immunotherapy. J Intern Med. 2002;251:272–277. 4. Buchs N, Chevrel G, Miossec P. Bacillus Calmette-Guérin induced aseptic arthritis: an experimental model of reactive arthritis. J Rheumatol. 1998;25:1662–1665. 5. Mas AJ, Romera M, Valverde Garcia J. Articular manifestations after the administration of intravesical ...