We consider an optimization deployment problem of multistatic radar system (MSRS). Through the antenna placing and the transmitted power allocating, we optimally deploy the MSRS for two goals: 1) the first one is to improve the coverage ratio of surveillance region; 2) the second goal is to get a even distribution of signal energy in surveillance region. In two typical working modes of MSRS, we...

PURPOSE Retinoids, a group of compounds, including vitamin A (retinol), and related metabolites, have been shown to regulate the growth and differentiation of many types of cells. IFN-alpha and either 13-cis-retinoic acid or liposomal all-trans retinoic acid have been used in the treatment of patients with metastatic renal cell carcinoma. We knew that samples from renal cell carcinomas containe...

Disturbed sarcoplasmic reticulum (SR) Ca content may underlie the altered force-frequency and postrest contractile behavior in failing human myocardium. We used rapid cooling contractures (RCCs) to assess SR Ca content in ventricular muscle strips isolated from nonfailing and end-stage failing human hearts. With an increase in rest intervals (1 to 240 s; 37°C), nonfailing human myocardium (n57)...

PURPOSE A disturbed myeloid lineage development with abnormally abundant neutrophils and impaired dendritic cell (DC) differentiation may contribute to tumor immune escape. We investigated the effect of sunitinib, a tyrosine kinase inhibitor of fms-like tyrosine kinase-3, KIT, and vascular endothelial growth factor receptors, on myeloid differentiation in renal cell cancer (RCC) patients. EXP...

The closed nature of geochemical data has been proven in many studies. Compositional data have special properties that mean that standard statistical methods cannot be used to analyse them. These data imply a particular geometry called Aitchison geometry in the simplex space. For analysis, the dataset must first be opened by the various transformations provided. One of the most popular of the a...

Renal cell carcinoma (RCC) accounts for 3% of adult deaths from cancer. The risk factors for its development are still under intense investigation. Although tobacco smoke is a risk factor, the data are inconsistent and the extent of the increased risk is unclear. Estimates from 19 case-control and 5 cohort studies were used. The case-control reports included 8,032 cases and 13,800 controls; the...

Kidney tumours form a broad spectrum of distinguished histopathological and molecular genetic entities. The last WHO classification is dated to 2004. Current classification has been published in October 2013 by ISUP (International Society of Urological Pathology). There were 5 new epithelials tumours: tubulocystic renal cell carcinoma (RCC), acquired cystic disease-associated RCC, clear cell (t...

THE STUDY OF THE ASSOCIATION OF DECAY RISK WITH MALOCCLUSIONS IN MIXED DENTITION AT CHILDREN FROM NORTHEAST ROMANIA. A TRANSVERSAL RETROSPECTIVE STUDY (Abstract): Aim. The purpose of this study was to investigate if high values of DMFT/dmft indices constitute risk factors for installation in various types of malocclusions in mixed dentition. Material and Methods The study consisted of 600 study...

Background Interferon-α (IFN-α) is one of the central agents in immunotherapy for renal cell carcinoma (RCC) and binds to the IFN-α receptor (IFNAR). We investigated the role of IFNAR in RCC. Methods We quantified IFNAR mRNA expression in paired tumor and nontumor samples from the surgical specimens of 103 consecutive patients with RCC using a real-time reverse transcription polymerase chain re...