Antitumor activity of spleen cells from BALB/c mice bearing RL male 1 lymphoma was studied. In the Winn assay spleen cells of the tumor-bearing mice inhibited the growth of RL male 1 lymphoma. This antitumor activity of spleen cells was not detected by the in vitro cell-mediated cytotoxicity assay (4-h 51Cr release assay). The effector cells in spleen cells were T-cells which manifested asialo ...

Comorbid chronic conditions are common among people with type 2 diabetes. We developed an artificial intelligence algorithm, based on reinforcement learning (RL), for personalized diabetes and multimorbidity management, strong potential to improve health outcomes relative current clinical practice. modeled glycemia, blood pressure, cardiovascular disease (CVD) risk as outcomes, using a retrospe...

A Raman Lidar (RL) system is developed to measure the water vapor mixing ratio (WVMR) and aerosol optical property in Wuhan with high temporal-spatial resolution during rainless nights. The principle of the self-developed lidar system and data processing method are discussed. WVMR profiles of a representative case retrieved by RL, Radiosonde (RS), and microwave radiometer (MR) are in good agree...

We address two problems in the field of automatic optimization of dialogue strategies: learning effective dialogue strategies when no initial data or system exists, and optimising dialogue management (DM) and Natural Language Generation (NLG) decisions in an integrated fashion. We use Reinforcement Learning (RL) to learn multimodal information presentation strategies through interaction with a ...

BACKGROUND Gemcitabine is an analogue of deoxycytidine with activity against several solid tumors. In order to elucidate the mechanisms by which tumor cells become resistant to gemcitabine, we developed the resistant subline RL-G from the human follicular lymphoma cell line RL-7 by prolonged exposure of parental cells to increasing concentrations of gemcitabine. RESULTS In vitro, the IC50 inc...

BACKGROUND To assess differences between four different voxel-based dosimetry methods (VBDM) for tumor, liver, and lung absorbed doses following (90)Y microsphere selective internal radiation therapy (SIRT) based on (90)Y bremsstrahlung SPECT/CT, a secondary objective was to estimate the sensitivity of liver and lung absorbed doses due to differences in organ segmentation near the liver-lung in...