Results 423 attendants completed the survey (response rate: 66%) of which 342 ICU nurses were included for further analysis. These are employed in general (73%) or university hospitals (27%) and are working in mixed (66%), surgical (18%) or medical (13%) ICUs. Short working agents are most frequently chosen for analgo-sedation. A majority of respondents administer sedatives in continuous infusi...

BACKGROUND Identifying risk factors for unplanned extubation in patients receiving mechanical ventilation can help guide prevention strategies. OBJECTIVE To assess the risk of unplanned extubation with different sedation strategies. METHODS A 36-month quality improvement study in a 33-bed intensive care unit at a tertiary-care center. RESULTS A total of 92 unplanned extubations occurred (...

BACKGROUND While mild and moderate sedation have been widely used to reduce sudden agitation in intracerebral hemorrhage (ICH) patients after surgery, agitation is still a frequent problem, which may cause postoperative blood pressure fluctuation. The present study aimed to evaluate the efficacy and safety of short-course deep sedation for the treatment of ICH after surgery. MATERIAL AND METHOD...

BACKGROUND Pain and agitation are common in patients after craniotomy. They can result in tachycardia, hypertension, immunosuppression, increased catecholamine production and increased oxygen consumption. Dexmedetomidine, an alpha-2 agonist, provides adequate sedation without respiratory depression, while facilitating frequent neurological evaluation. METHODS/DESIGN The study is a prospective...

IMPORTANCE Protocolized sedation improves clinical outcomes in critically ill adults, but its effect in children is unknown. OBJECTIVE To determine whether critically ill children managed with a nurse-implemented, goal-directed sedation protocol experience fewer days of mechanical ventilation than patients receiving usual care. DESIGN, SETTING, AND PARTICIPANTS Cluster randomized trial cond...

To observe the analgesic and sedative effect of remifentanil in patients with mechanical ventilation intensive care unit to explore application value ventilation. 164 were randomly divided into combined dexmedetomidine group (R group), sufentanil (S group) where 82 each group. The two groups assessed pain observation instrument (critical tool) for analgesia score was Ramsay scale. vital signs d...

Optimal management of sedation, pain, agitation, and delirium in intensive care unit (ICU) involves systematic and multimodal approaches to provide comfort and safety. As one of the most widely used alpha 2-adrenergic receptor agonists, dexmedetomidine has become more and more popular for sedation and agitation in critically ill adult patients. The sedative, analgesic and opioid-sparing effects...

Methods Prospective single centre observational study (Feb 2014 to Jan 2015). Eligible patients were physically restrained while receiving mechanical ventilation. Psychotropic drug data were collected 1 hour before PR and for 6 hours after PR. We recorded PR indications, psychotropic drug interventions including new drug initiation, dose increase, dose decrease, and drug cessation. We documente...

BACKGROUND Adequate sedation is important in the post-anesthesia care unit (PACU) following uvulopalatopharyngoplasty (UPPP) to ensure patient comfort and decrease the duration of mechanical ventilation (MV), PACU stay, and bleeding. This study aimed to compare dexmedetomidine and propofol as sedatives after UPPP in the PACU. MATERIAL AND METHODS We randomized 124 mechanically ventilated adul...