The oxidative hemolysis of rat erythrocytes induced by 2,2’-azobis–(2-amidinopropane) (AAPH) and its inhibition by rosemary essential oil was studied. Different concentrations (0.178, 0.357, 0.534 and 0.712 ml/ml) of the essential oil showed no significant hemolysis compared to phosphate buffer solution. AAPH (25 mM and 50 mM) induced hemolysis in a time-dependent manner. Diff e r e n t ...

Aiming to contribute to the development of alternative control methods of the coffee leaf miner, Leucoptera coffeella (Guérin-Mèneville & Perrottet, 1842) (Lepidoptera: Lyonetiidae), a search for plants able to produce active substances against this insect was carried out, with species collected during different periods of time in the Alto Rio Grande region, (Lavras, Minas Gerais, Brazil). Coff...

In this paper we use three disparate examples to highlight the relevance of historical methods in the context of ethnobotany and ethnopharmacology. Unfortunately, in ethnopharmacology we have only very few examples where such historical depth is possible. On the other hand the first hand data available through ethnopharmacological research, may be of relevance for interpreting historical inform...

Rosemary (Rosmarinus officinalis L.) has always known a versatile, aromatic herb and addition to being used as a food flavoring is also known medicinally for its powerful antioxidant activity, antibacterial and hepatoprotective properties. In this study we examined the effects of rosemary iextract on the lifespan and aging in Drosophila melanogaster against high-fat induced oxidative injury, an...

Rosemary extracts containing the phenolic diterpenes carnosic acid and its derivative carnosol are approved food additives used in an increasingly wide range of products to enhance shelf-life, thanks to their high anti-oxidant activity. We describe here the elucidation of the complete biosynthetic pathway of carnosic acid and its reconstitution in yeast cells. Cytochrome P450 oxygenases (CYP76A...

The antifungal activity and the chemical composition of essential oils (EOs) from some Mediterranean autochthonous plants were investigated against Malassezia pachydermatis, a fastidious opportunistic yeast usually involved in canine external otitis. Minimum inhibitory concentrations (MICs) of Anthemis nobilis, Citrus limon, Citrus paradisi, Illicium verum, Lavandula hybrida, Mentha piperita, O...

background: rosemary (rosmarinus officinalis l.) as a member of the lamiaceae family is a valuable aromatic and medicinal plant which is cultivated in large scale in iran. therefore, it is necessary to determine influence of factors affecting plant growth and drug metabolite production. objectives: this experiment was carried out to evaluate the effects of bio-stimulators compounds on growth an...

Background The aim of present study was to evaluate antileishmanial effects of Lavandula angustifolia (L. angustifolia) and Rosmarinus officinalis (R. officinalis) medicinal plants essential oils and nano-emulsions on Leishmania major (L. major). Methods The present study was performed in Leishmaniasis Reference Lab at Mazandaran University of Medical Sciences, Iran during 2016-2017. The IC50...