This paper presents an optimum design of a photovoltaic (PV) power system for the satellite market using high efficiency solar cells. This is to enhance the power capabilities of the satellite solar arrays without extra challenges in area, weight and budget constraints. In this way, the designed power system can efficiently fulfill the power requirements of the satellite subsystems, either in d...

Precise control of the thyroid hormone (T3)-dependent transcriptional program is required by multiple cell systems, including muscle stem cells. Deciphering how this is achieved and how the T3 signal is controlled in stem cell niches is essentially unknown. We report that in response to proliferative stimuli such as acute skeletal muscle injury, type 3 deiodinase (D3), the thyroid hormone-inact...

The composition of the extracellular matrix (ECM) of skeletal muscle fibers is a unique environment that supports the regenerative capacity of satellite cells; the resident stem cell population. The impact of environment has great bearing on key properties permitting satellite cells to carry out tissue repair. In this study, we have investigated the influence of the ECM and glycolytic metabolis...

Regeneration of muscle fibres following injury requires the activation of quiescent satellite cells, their proliferation and finally their differentiation and fusion into multi-nucleated myotubes which will, after maturation, replace the damaged fibre. Although many reports have been published concerning the differentiation potential of satellite cells in vitro, and the formation of new fibres ...

Satellite cell activity is necessary for postnatal skeletal muscle growth. Severe phosphate (PO(4)) deficiency can alter satellite cell activity, however the role of neonatal PO(4) nutrition on satellite cell biology remains obscure. Twenty-one piglets (1 day of age, 1.8 ± 0.2 kg BW) were pair-fed liquid diets that were either PO(4) adequate (0.9% total P), supra-adequate (1.2% total P) in PO(4...

Skeletal muscle postnatal growth and repair depend on satellite cells and are regulated by molecular signals within the satellite cell niche. We investigated the molecular and cellular events that lead to altered myogenesis upon genetic ablation of Syndecan-3, a component of the satellite cell niche. In the absence of Syndecan-3, satellite cells stall in S phase, leading to reduced proliferatio...

Muscle fiber number is determined around the time hatch with continued posthatch muscle growth being mediated by the adult myoblast, satellite cell, population of cells. Satellite cells are dynamic in their expression of proteins including the cell membrane associated proteoglycans, syndecan-4 and glypican-1. These proteoglycans play roles in organizing the extracellular environment in the sate...

Satellite cells are considered to be adult skeletal muscle stem cells. Their ability to regenerate large muscle defects is highly dependent on their specific niche. When these cells are cultured in vitro, the loss of this niche leads to a loss of proliferative capacity and defective regeneration when implanted back into a muscle defect. The most important aspects of the niche will be discussed-...

Skeletal muscle possesses a remarkable ability for regeneration and can go through rapid repair following muscle injury. This regeneration depends on the activity and contributions of muscle satellite cells, which are located between the sarcolemma of myofibers and the basal lamina [1]. Upon muscle injury, satellite cells are activated, driven out of their quiescent state, and start to prolifer...