OBJECTIVES To identify and compare the gene expression profiles of actinic keratosis (AK) and squamous cell carcinoma (SCC) and to further clarify critical genetic alterations in the evolution of SCC from normal sun-damaged human skin. DESIGN Observational study. SETTING University practice. PATIENTS Skin biopsy specimens were obtained from 16 patients. The specimens included 14 normal no...

Background Although squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) can be easily diagnosed clinically, proper diagnosis is sometimes difficult when based on clinical information alone. Objective To know what causes clinical misdiagnosis between SCC and BCC, and evaluate whether dermoscopy can improve diagnostic accuracy. Methods Clinical and dermoscopic photographs of inversel...

BACKGROUND To investigate the significance of monitoring the levels of the serum squamous cell carcinoma antigen (SCC-Ag) for the detection of recurrent disease in patients with cervical cancer treated by concurrent chemoradiotherapy. METHODS The records of 112 patients with cervical cancer were reviewed. Serum SCC-Ag levels were measured at regular follow-up visits. A SCC-Ag level of 2 ng/mL...

Squamous cell carcinoma (SCC) and adenocarcinoma (AC) are the major histological types of non-small cell lung carcinoma (NSCLC). Although both SCCs and ACs have been characterized histologically and clinically, the precise mechanisms underlying their migration and invasion are not yet known. Here, we address the involvement in NSCLC of the p21-associated kinase1 (Pak1)/LIM kinase1 (LIMK1)/cofil...

Prediction of SCC risk of austenitic stainless steels in aqueous chloride solution and estimation of the time to failure as a result of SCC form important and complicated topics for study. Despite the many studies reported in the literature, a formulation or a reliable method for the prediction of time to failure as a result of SCC is yet to be developed. This paper is an &#10effort to investig...

Background & Objective: Squamous cell carcinoma (SCC) is the second most common non-melanoma skin cancer that may be caused by Human papillomavirus (HPV), especially in immunosuppressed patients. However, the role of the mucosal types of HPV in SCC patients with normal immunity has not been extensively confirmed. The aim of this study was to investigate the association...

Background: Cognitive functioning is important for managing work and life in general. Some experience problems with cognitive functioning, often referred to as subjective cognitive complaints (SCC). These problems are rather prevalent in the working population and can be coupled with both lowered well-being and work ability. However, the relation between SCC and memory functioning across the ad...

Self-consolidating concrete (SCC) has been developed for use in precast prestressed concrete bridge girders in the state of Minnesota. Locally available materials were used with a number of cementitious and filler materials, including ASTM Type III cement, Class C fly ash, and blast furnace slag. SCC was successfully proportioned with both natural river gravels and crushed stone as coarse aggre...

Previous molecular genetic studies of laryngeal squamous cell carcinoma (SCC)have shown certain chromosomal regions with recurring alterations. But studies of sequential molecular alterations and genetic progression model of laryngeal SCC have not been clearly defined. To identify the chromosomal alterations associated with the carcinogenesis of laryngeal SCC, we analyzed genomic DNA from micro...

Squamous cell lung cancer (SCC) represents an area of unmet need in lung cancer research. For the past several years, therapeutic progress in SCC has lagged behind the now more common non-small cell lung cancer histologic subtype of adenocarcinoma. However, recent efforts to define the complex biology underlying SCC have begun to bear fruit in a multitude of ways, including characterization of ...