BACKGROUND Nucleosome translocation along DNA is catalyzed by eukaryotic SNF2-type ATPases. One class of SNF2-ATPases is distinguished by the presence of a C-terminal bromodomain and is conserved from yeast to man and plants. This class of SNF2 enzymes forms rather large protein complexes that are collectively called SWI/SNF complexes. They are involved in transcription and DNA repair. Two broa...

BACKGROUND Microscopy-based identification of eggs in stool offers simple, reliable and economical options for assessing the prevalence and intensity of hookworm infections, and for monitoring the success of helminth control programs. This study was conducted to evaluate and compare the diagnostic parameters of the Kato-Katz (KK) and simple sodium nitrate flotation technique (SNF) in terms of d...

One dairy goat herd of mixed breeds was investigated for frequency of genetic variants of alphas1-casein (as1-CN) and relationships between the genetic variants, milk composition, coagulation properties, and breed. Milk composition (percent total solids, solids-non-fats (SNF), fat, protein, casein, and as1-CN), genetic variants of as1-CN, and coagulation properties (coagulation time, coagulatio...

OBJECTIVES To characterize the care received by skilled nursing facility (SNF/NF) patients suffering cardiac arrest and to evaluate the outcome of SNF/NF patients experiencing cardiac arrest. DESIGN A retrospective analysis of an existing cardiac arrest registry to characterize SNF/NF cardiac arrest patients and to compare them to community-dwelling cardiac arrest patients was performed. SE...

SWI/SNF complexes utilize BRG1 (also known as SMARCA4) or BRM (also known as SMARCA2) as alternative catalytic subunits with ATPase activity to remodel chromatin. These chromatin-remodeling complexes are required for mammalian development and are mutated in ~20% of all human primary tumors. Yet our knowledge of their tumor-suppressor mechanism is limited. To investigate the role of SWI/SNF comp...

Context: COVID-19 exerted severe challenges on skilled nursing facility (SNF) residents and staff. A combination of internal external factors predisposed SNFs to an increased propensity spread. Objective: The purpose this paper is examine which characteristics may have contributed outbreaks within urban rural North Dakota facilities. Methods: 23-question survey regarding was developed distribut...

Background and Objectives: Canola oil is very low in saturated fatty acid (~8 %), which makes it suitable for application as dressing for salad. Canola oil is liquid, thus its application in the production of margarine and shortening is limited. The present study provides information about the effects of monoacylglycerols (MAG) as the structuring agent on physical, microstructure and rheologica...

The aim of the study was to assess values and correlations between selected markers acid-base balance electrolytes in blood late lactation cows, such as pH, pCO2, pO2, HCO3 –, BE, BE(B), Na+, K+, Cl–, well parameters milk, number somatic cells (SCC), colony forming units (CFU), milk fat (MF), protein (MP), lactose (ML), solids, solids non-fat (SNF), current production. Blood samples were collec...

As hospitals are increasingly held accountable for patients' post-discharge outcomes under new payment models, hospitals may choose to acquire skilled nursing facilities (SNFs) to better manage these outcomes. This raises the question of whether patients discharged to hospital-based SNFs have better outcomes. In unadjusted comparisons, hospital-based SNF patients have much lower Medicare utiliz...

To investigate the mechanism of SWI/SNF action, we have analyzed the pathway by which SWI/SNF stimulates formation of transcription factor-bound nucleosome core complexes. We report here that the SWI/SNF complex binds directly to nucleosome cores and uses the energy of ATP hydrolysis to disrupt histone/DNA interactions, altering the preferred path of DNA bending around the histone octamer. This...