نتایج جستجو برای: sporadic prostate cancer
تعداد نتایج: 951267 فیلتر نتایج به سال:
Background: Transrectal ultrasonography guided needle biopsy of prostate frequently used for early detection of cancer has faced the pathologists with a major diagnostic challenge. In recent years P504S has been used as a tumor cell marker for definitive diagnosis of prostatic cancer in small biopsy specimens.Methods: 70 prostate needle biopsies and 6 transurethral resections (TURP) containing ...
background: androgen receptors (ar) play an important role in proliferation of cancerous prostatic cells and prevention of apoptotic signaling. current drugs cannot inhibit the activity of these receptors very well. establishment of appropriate animal models is essential for discovery of new drugs of target therapy in hormone dependent prostate cancer. materials and methods: standard prostatic ...
PTEN frequently shows loss of heterozygosity in breast and prostate cancers, and mutations in this gene are responsible for Cowden disease, a rare Mendelian syndrome that includes breast cancer as part of its phenotype. Thus, PTEN serves as a candidate susceptibility gene for both breast and prostate cancer risk. Whether common inherited variation (either coding or noncoding) at the PTEN locus ...
background : a transrectal ultrasound-guided prostate biopsy is currently the gold standard procedure to detect prostatic adenocarcinoma. there is little information on the clinical utility of this technique for the detection of prostate adenocarcinoma in men with suspected prostate cancer in pakistan. this study seeks to determine the frequency of prostatic adenocarcinoma by using a transrecta...
background: stereotactic body radiotherapy (sbrt) has emerged as an effective treatment for localized prostate cancer. however, prostate-specific antigen (psa) kinetics after sbrt has not been well characterized. the objective of the current study is to analyze the rate of psa decline and psa nadir following hypofractonated sbrt in localized prostate cancer. materials and methods: from 2008 to ...
A combination of genetic and epigenetic factors may explain the disproportionate incidence and mortality of prostate cancer among African-American males (AAMs) as compared with Caucasian American males (CAMs). We wished to determine whether primary prostate cancers from AAMs and CAMs harbor different patterns or frequencies of chromosomal alterations. Comparative genomic hybridization (CGH) was...
ABSTRACT Prostate specific antigen (PSA) is a specific marker of prostate tumor which is used for diagnosis of prostate cancer. Apart from prostate cancer,different factors may affect PSA level and ejaculation is one of these possible factors .In a study on 21 patients at ages of 18-37, serum levels of PSA were measured before the ejaculation and about two hours after it. There was no statisti...
Abstract Background: Removal of prostate and radiotherapy are used routinely for treatment of prostate cancer however in advanced stages of the disease these treatments are ineffective. Researchers are exploring strategies for preventing this malignancy. This study aims to design and develop a phage based vaccine for preventing prostate cancer. Materials and methods: After conducting bioinforma...
Abstract Background: Since hydro-alcohol concentration of Thymus Vulgaris plays a role in prevention of any growth disorders and separation of cells and cancer, therefore this research intends to study the effect of mentioned concentration and DMBA (a type of chemical cancer factor) on the weight and histo-pathologic properties of prostate of the desert mouse–Wistar race. Materials and meth...
Background: Prostate cancer is the second most prevalent canceramong men and the eighth leading cause of death in Iran. In pathological conditions, angiogenesis increases the chance of metastasis and thus spreads cancer. The aim of the present study was to examine the effects of 10 weeks of resistance training on some angiogenesis factors among men affected by prostate cancer. Materials and Me...
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