Objective: The study aims to investigate the diagnostic value of hemogram derived systemic inflammation parameters in ovarian cancer.Methods: Totally, group consisted 60 patients with suspected masses who underwent surgery between February 1th, 2020, and May 2021, Ordu University Training Research Hospital. included were divided into two groups according postoperative histopathological diagnosi...

UNLABELLED Procalcitonin has been shown to be useful in separating infection from non-infective disorders. However, infection is often paralleled by tissue inflammation. Most studies supporting the use of procalcitonin were confounded by more significant inflammation in the infection group. Few studies have examined the usefulness of procalcitonin when adjusted for inflammation.Pleural inflamma...

Steiner AA, Oliveira DL, Roberts JL, Petersen SR, Romanovsky AA. Nicotine administration and withdrawal affect survival in systemic inflammation models. J Appl Physiol 105: 1028–1034, 2008. First published July 10, 2008; doi:10.1152/japplphysiol.90619.2008.—How different regimens of nicotine administration and withdrawal affect systemic inflammation is largely unknown. We studied the effects of...

How different regimens of nicotine administration and withdrawal affect systemic inflammation is largely unknown. We studied the effects of chronic and acute nicotine administration and of nicotine withdrawal on the outcome of aseptic and septic systemic inflammation. Male C57BL/6 mice were implanted with subcutaneous osmotic pumps (to deliver nicotine) and intrabrain telemetry probes (to measu...

BACKGROUND During systemic inflammation, leucocytes are activated and extravasate into damaged tissue. Activation and recruitment are influenced by different mechanisms, including the interaction of leucocytes with platelets and neutrophil extracellular traps (NET) formation. Here, we investigated the molecular mechanism by which hydroxyethyl starch (HES 130/0.4) dampens systemic inflammation i...

UNLABELLED Microglia play an essential role in many brain diseases. Microglia are activated by local tissue damage or inflammation, but systemic inflammation can also activate microglia. An important clinical question is whether the effects of systemic inflammation on microglia mediate the deleterious effects of systemic inflammation in diseases such as Alzheimer's dementia, multiple sclerosis,...