نتایج جستجو برای: targeted gene therapy
تعداد نتایج: 1818842 فیلتر نتایج به سال:
Adv. Funct. Mater. 2018, 28, 1800173 In the initially published version of this article, H&E images in Supplementary Figure 4E are incorrect. The errors were introduced at time figure assembly. corrected 4 is given below. None conclusions main text affected by correction. authors apologize for any inconvenience or misunderstanding that may have caused.
Abstract Background Effective methods to deliver therapeutic genes solid tumors and improve their bioavailability are the main challenges of current medical research on gene therapy. The development efficient non-viral vector with tumor-targeting has very important application value in field cancer Proteolipid integrated potential functional protein excellent delivery performance shown for targ...
Molecular-focused cancer therapies, e.g., molecularly targeted therapy and immunotherapy, so far demonstrate only limited efficacy in cancer patients. We hypothesize that underestimating the role of biophysical factors that impact the delivery of drugs or cytotoxic cells to the target sites (for associated preferential cytotoxicity or cell signaling modulation) may be responsible for the poor c...
BACKGROUND To assess the efficacy profile of erlotinib-based doublet targeted therapy compared with erlotinib monotherapy for previously treated patients with advanced NSCLC, a meta-analysis was performed. PATIENTS AND METHODS We rigorously searched PubMed, Embase, Cochrane and meeting proceedings. Phase II/III randomized trials reporting on the efficacy of erlotinib-doublet therapy versus si...
The cerebellum plays an important role in coordinated movement, motor learning and vestibular function. Cerebellar damage results in impaired body balance and disturbance in gait and posture. The cerebellum is impaired by various genetic diseases, such as spinocerebellar ataxia and mucopolysaccharidosis, and these diseases could be good candidates for gene therapy. There are at least two challe...
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