نتایج جستجو برای: term stability of formulation m1
تعداد نتایج: 21233874 فیلتر نتایج به سال:
abstract venlafaxine, 1–[2–(dimethylamino)–1–(4–methoxyphenyl) ethyl]cyclohexanol hydrochloride is a novel non-tricyclic antidepressant. venlafaxine is a second generation antidepressant drug, has a neuropharmacologic profile distinct from that of existing antidepressants including tricyclic compounds, selective serotonin reuptake inhibitors and monoamine oxidase inhibitors. venlafaxine impart...
Fast disintegrating tablets of lorazepam were prepared by effervescent method with a view to enhance patient compliance. A 3(2) full factorial design was applied to investigate the combined effect of two formulation variables: amount of crospovidone and mixture of sodium bicarbonate, citric acid and tartaric acid (effervescent material) on in vitro dispersion time. Crospovidone (2-8% w/w) was u...
although some 3d slope stability algorithms have been proposed in recent three decades, still role of pore pressures in three dimensional slope stability analyses and considering the effects of pore water pressure in 3d slope stability studies needs to be investigated. in this paper, a limit analysis formulation for investigation of role of the pore water pressure in three dimensional slope sta...
Presynaptic m1 muscarinic receptors are necessary for mGluR long-term depression in the hippocampus.
To investigate the role of M1 muscarininc acetylcholine receptors (m1 receptors) in metabotropic glutamate receptor (mGluR)-mediated long-term depression (LTD), we produced mouse lines in which deletion of the m1 gene is restricted to the forebrain (FB-m1KO) or hippocampal CA3 pyramidal neurons (CA3-m1KO). Stimulation in FB-m1KO hippocampal slices resulted in excitatory postsynaptic potentials ...
Objectives: To investigate the effectiveness of a controlled accelerated short-term lumbar stabilizing exercises on postural indices and limit of stability in patients with non specific chronic low back pain. Materials & Methods: A sample of convenience of 20 patients with nonspecific chronic low back pain participates in this pretest – posttest study. Postural control indices including Ove...
BACKGROUND Data on contributors to between-individual variability in overall tramadol clearance and O-demethyl tramadol (M1) formation in preterm neonates and young infants are limited. METHODS A population pharmacokinetic analysis of tramadol and M1 was undertaken using non-linear mixed effects model. Covariate analysis included weight, postmenstrual age (PMA), postnatal age (PNA), creatinae...
in fact, this study focused on the following questions: 1. is there any difference between the effect of functional/notional approach and the structural approaches to language teaching on the proficiency test of efl learners? 2. can a rather innovative language test referred to as "functional test" ge devised so so to measure the proficiency test of efl learners, and thus be as much reliable an...
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