this study aimed to determine the effectiveness of schema therapy in the treatment of social anxiety disorder. method: the research method was a single-case experimental design with multiple baselines. five clients were selected by purposive sampling method. they were received 20 individual sessions based on young's schema therapy model. the social phobia inventory (spin), liebowitz social anxi...

one of the common chronic inflammatory skin diseases is acne vulgaris that affects up to 80% of a teen-age population. the progress of acne lesions is due to colonization of propionibacterium acnes (p .acnes) in hair follicles. treatment of acne includes topical or systemic therapy or combination therapy, with a tendency to perform topical therapy in mild to moderate acne. nanoemulsions, small ...

Introduction: This study set out to investigate the efficacy of training through emotion-focused therapy (EFT) on the improvement of marital passion. Correspondence: Mohammad Baghban, PhD Student. Young Researchers and Elite Club Islamic Azad University, Marvdasht Branch. Marvdasht, Iran Tel:+9...

Specific delivery of therapeutic agents to solid tumors and their bioavailability at the target site are the most clinically important and challenging goals in cancer therapy. Liposomes are promising nanocarriers and have been well investigated for cancer therapy. In spite of preferred accumulation in tumors via the enhanced permeability and retention (EPR) effect, inefficient drug release at t...

Synergistic Therapy In article number 2101155, Yujun Song, Zhengbao Zha, Xin Han, and co-workers report a novel thermo-responsive nanotherapeutic platform, which is triggered by 808 nm near-infrared light irradiation. This exogenously controlled method can be used in combination tumor therapy, including gene-therapy, mild-photothermal chemotherapy, provides versatile strategy for gene editing d...

Significant advances in therapy for lysosomal storage disorders have occurred with an accelerating pace over the past decade. Although enzyme replacement therapy has improved the outcome of lysosomal storage disorders, antibody responses have occurred and sometimes prevented efficacy, especially in cross-reacting immune material negative patients with Pompe disease. Preclinical gene therapy exp...

gene therapy consists of the introduction of genetic material into cells for a therapeutic purpose. the understanding of the basics of the molecular and cellular mechanisms in disease treatments has resulted in the development of high-tech gene transfer materials with improved therapeutic efficacy. based on the results of more than 2000 clinical trials to date, gene therapy is going to be inclu...