BACKGROUND/AIM Thyroid associated orbitopathy (TAO) and Graves' disease (GD) have an autoimmune pathogenesis, possibly related to the thyrotropin receptor (TSHR). The aim of this study was to determine whether TSHR immunoreactivity is correlated with disease severity or serum TSHR antibody (TRAB) levels. METHODS Orbital tissues from 30 patients with TAO were compared with those of 20 patients...

Hashitoxicosis is a transient period of hyperthyroid state in patient with Hashimoto thyroiditis. Ii not common condition. Exophthalmos usually bilateral disease commonly associated Graves's hyperthyroidism. It rarely occurs thyroiditis or hashitoxicosis. Unilateral exophthalmos less presentation ophthalmopathy. So, we present this case male thyroiditis, who presented unilateral and Hashitoxico...

AIMS We compared the effects of total thyroidectomy (TTx) and radioiodine (RAI) administration on the course of thyroid hormones and thyroid-stimulating immunoglobulins (TSI) in patients with Graves' disease. METHODS We retrospectively studied 80 patients initially treated with antithyroid drugs and requiring either RAI (8.3 ± 1.7 mCi of (131)I; n = 40) or TTx (n = 40) as second-line therapy....

1Division of Endocrinology and Metabolism, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka 830-0011, Japan 2Department of Medicine, Nepean Clinical School, Nepean Hospital, The University of Sydney, Penrith, NSW 2751, Australia 3Molecular Thyroid Research Laboratory, Department of Medicine I, Johannes Gutenberg University (JGU) Medical Center, 55101 Mainz, Germany ...

Purpose: The aim of this study is to evaluate the findings optical coherence tomography, visual field and orbital computerized tomography in thyroid eye disease, correlate with clinical data for early detection anticipation dysthyroid optic neuropathy.
 Setting Design: This a comparative observational cross-sectional that was conducted at Outpatient Clinic Ophthalmology Department Tanta Un...

Objectives: To determine the occurrence and severity of thyroid eye disease regarding function in patients with autoimmune (AITD).
 Study Design: Cross-sectional study.
 Place Duration Study: Endocrinology Clinics, Jinnah Postgraduate Medical Centre (JPMC) Medicell Institute Diabetes & Metabolism (MIDEM) Karachi Pakistan, from Jan to Dec 2020.
 Methodology: Patients AITD or p...