In recent years we have seen an important increase in the number of protonated molecules detected cold dense clouds. Here report detection TMC-1 HCCNCH+, form HCCNC, which is a metastable isomer HC3N. This first cloud. The was based on observations carried out with Yebes 40m and IRAM 30m telescopes, revealed four harmonically related lines. We derive rotational constant B = 4664.431891 +/- 0.00...

  Objective(s): The objective of this study was to design a topical microemulsion of Vit B12 and to study the correlation between internal structure and physicochemical properties of the microemulsions. Microemulsions are thermodynamically stable mixtures of water, oil, surfactants and usually cosurfactants with several advantages for topical and transdermal drug delivery. The formul...

Background: The present study aimed to investigate the equivalent dose in vital organs, including heart and lung, due to secondary particles produced during breast proton therapy. Materials and Methods: The numerical ORNL female-phantom was improved and simulated using the Monte Carlo MCNPX code. The depth-dose profile of proton beams with different energies was simulated. The proper energy ran...

One advantage of using protons for signaling and regulation as opposed to posttranslational modifications or cofactors is the potential for extremely rapid temporal responses. Protons can diffuse through water exceptionally quickly (“Grotthuss diffusion,” made possible in part by the quantum mechanical tunneling ability of protons), possibly facilitated by short-range motion in proteins (58). T...

background: the purpose of this paper is to establish an easy and reliable biodosimeter protocol to evaluate the biological effects of proton beams. materials and methods: human peripheral blood lymphocytes were irradiated using proton beams (let: 34.6 kev μm−1), and the chromosome aberrations induced were analyzed using cytokinesis-blocked (cb) micronucleus (mn) assay. to determine the efficie...

Introduction Proton therapy is used to treat malignant tumors such as melanoma inside the eye. Proton particles are adjusted according to various parameters such as tumor size and position and patient’s distance from the proton source. The purpose of this study was to assess absorbed doses in eyes and various tumors found in the area of sclera and choroid and the adjacent tissues in radiotherap...

The optimized geometries, harmonic vibrational frequencies, and energies of the structures of monohydrated alloxan were computed at the DFT/ωB97X-D and B3LYP/6-311++G** level of theory. Results confirm that the monohydrate exists as a dipolar alloxan-water complex which represents a global minimum on the potential energy surface (PES). Trajectory dynamics simulations show that attempt to reorie...

This review focuses on the detailed characterization of proton and metal reactivity on the surface of bacteriogenic iron oxides (BIOS). This substance is composed of a highly porous matrix of ferrihydrite intermixed with intact and fragmented Gallionella ferruguinea cells. Studies concerning proton and metal cation binding to the BIOS were designed to assess their surface chemical heterogeneity...

In this paper, the study of melatonin and 60 meta- and ortho-substituted melatonins is presented. The reaction enthalpies related to the hydrogen atom transfer (HAT), single electron transfer - proton transfer (SET-PT) and sequential proton loss electron transfer (SPLET) have been calculated using DFT/B3LYP method in gas-phase and water. Results show that electron-withdrawing substituents incre...